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Titolo:
Colorectal cancer screening through detection of fecal occult blood in a controlled health zone
Autore:
Tarraga, P; Garcia-Olmo, D; Celada, A; Garcia-Molinero, MJ; Divison, JA; Casado, C;
Indirizzi:
Albacete Gen Hosp, Casas Ibanez Hlth Ctr, Albacete, Spain Albacete Gen Hosp Albacete Spain Casas Ibanez Hlth Ctr, Albacete, Spain
Titolo Testata:
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
fascicolo: 5, volume: 91, anno: 1999,
pagine: 340 - 344
SICI:
1130-0108(199905)91:5<340:CCSTDO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTROLLED TRIAL; HEMOCCULT; SENSITIVITY; SPECIFICITY;
Keywords:
colorectal cancer; early diagnosis; screening;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Tarraga, P Ctr Salud Casas Ibanez, C Villamalea S-N, Casas Ibanez 02200, Albacete, Spain Ctr Salud Casas Ibanez C Villamalea S-N Casas Ibanez Albacete Spain 02200
Citazione:
P. Tarraga et al., "Colorectal cancer screening through detection of fecal occult blood in a controlled health zone", REV ESP E D, 91(5), 1999, pp. 340-344

Abstract

AIM: to determine the viability and utility of fecal occult blood (FOB) screening (Hemoccult Ii) as a method for the early diagnosis of colorectal cancer in a well-controlled health area. METHODS: between February 1994 and September 1996, personal. letters were sent to all persons in the Casas Ibanez health area (Albacete) aged between50 and 75 years (4986 persons). All the tests were read by the same team member. A clinical history was taken of persons with positive test results, and they were offered colonoscopy. If a growth was found which was suitablefor endoscopic resection, this was done. If the growth was totally resected an annual check-up was advised. Malignant and partially resected premalignant growths were referred for surgical treatment. We analyzed percent participation, attendance for testing, negative and positive tests, growths diagnosed, false-positive tests and positive predictive value. RESULTS: the a participation rate was 56.25%. In the 157 colonoscopies performed, 39 neoplasic polyps and 9 cancers were found (7 of which were Dukesstage A and 2 of which were Dukes stage C-D). Sensitivity was 97% and specificity was 96%. The positive predictive value was 30.37%. The positivity rate was 6.08%, while the predictive,value for cancer was 5.38% and the predictive value for adenoma was 23.35%. CONCLUSIONS: FOB screening, in our setting, proved to have a high recruitment capacity with a positive predictive value for colorectal carcinoma which was slightly higher than the value obtained in other countries of similarsocioeconomic status. Furthermore, we found a significant improvement in the diagnostic stage of colorectal carcinoma at the time of resection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:20:17