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Titolo:
Effects of sleep deprivation: The phosphorus metabolism in the human brainmeasured by P-31-magnetic resonance spectroscopy
Autore:
Murashita, J; Yamada, N; Kato, T; Tazaki, M; Kato, N;
Indirizzi:
Shiga Univ Med Sci, Dept Psychiat, Shiga 5202121, Japan Shiga Univ Med Sci Shiga Japan 5202121 pt Psychiat, Shiga 5202121, Japan Univ Tokyo, Fac Med, Dept Neuropsychiat, Tokyo, Japan Univ Tokyo Tokyo Japan Tokyo, Fac Med, Dept Neuropsychiat, Tokyo, Japan Shiga Mental Hlth Ctr Hosp, Shiga, Japan Shiga Mental Hlth Ctr Hosp Shiga Japan ntal Hlth Ctr Hosp, Shiga, Japan
Titolo Testata:
PSYCHIATRY AND CLINICAL NEUROSCIENCES
fascicolo: 2, volume: 53, anno: 1999,
pagine: 199 - 201
SICI:
1323-1316(199904)53:2<199:EOSDTP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Keywords:
depression; frontal lobes; magnetic resonance spectroscopy; sleep deprivation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Murashita, J Shiga Univ Med Sci, Dept Psychiat, Shiga 5202121, Japan ShigaUniv Med Sci Shiga Japan 5202121 Shiga 5202121, Japan
Citazione:
J. Murashita et al., "Effects of sleep deprivation: The phosphorus metabolism in the human brainmeasured by P-31-magnetic resonance spectroscopy", PSY CLIN N, 53(2), 1999, pp. 199-201

Abstract

Sleep deprivation (SD) has an antidepressant effect in some, but not all, patients with depression, although its biological mechanisms have not yet been characterized. We previously reported altered brain phosphorus metabolism measured by phosphorus-31 magnetic resonance spectroscopy (P-31-MRS) in patients with bipolar depression. We preliminarily examined effects of SD on phosphorus metabolism in the frontal lobes of 15 normal subjects using P-31-MRS. No significant differences of membrane phospholipid metabolism high-energy phosphate metabolism and intracellular pH were found between beforeand after SD in these subjects. Further studies will be necessary to elucidate the physiological mechanism of SD for depressive patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 01:59:33