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Titolo:
Thallium-201 single-photon emission computed tomographic and proton magnetic resonance spectroscopic characteristics of intracranial ganglioglioma: Three technical case reports
Autore:
Kumabe, T; Shimizu, H; Sonoda, Y; Shirane, R;
Indirizzi:
Tohoku Univ, Sch Med, Dept Neurosurg, Aoba Ku, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 Ku, Sendai, Miyagi 9808574, Japan Kohnan Hosp, Dept Neurosurg, Sendai, Miyagi, Japan Kohnan Hosp Sendai Miyagi Japan p, Dept Neurosurg, Sendai, Miyagi, Japan
Titolo Testata:
NEUROSURGERY
fascicolo: 1, volume: 45, anno: 1999,
pagine: 183 - 187
SICI:
0148-396X(199907)45:1<183:TSECTA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANAPLASTIC GANGLIOGLIOMA; CEREBRAL GANGLIOGLIOMAS; MR SPECTROSCOPY; TL-201; TUMORS; MALIGNANCY;
Keywords:
ganglioglioma; proton magnetic resonance spectroscopy; Thallium-201 single-photon; emission computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Kumabe, T Tohoku Univ, Sch Med, Dept Neurosurg, Aoba Ku, 1-1 Seiryo Machi,Sendai, Miyagi 9808574, Japan Tohoku Univ 1-1 Seiryo Machi Sendai Miyagi Japan 9808574 , Japan
Citazione:
T. Kumabe et al., "Thallium-201 single-photon emission computed tomographic and proton magnetic resonance spectroscopic characteristics of intracranial ganglioglioma: Three technical case reports", NEUROSURGER, 45(1), 1999, pp. 183-187

Abstract

OBJECTIVE: The correlation between thallium-201 (Tl-201) uptake, semiquantitative choline-containing compound values measured by proton magnetic resonance spectroscopy (H-1-MRS), and Ki-67 labeling indexes (LIs) was investigated in three gangliogliomas. METHODS: The early and delayed Tl-201 indexes were calculated as the ratioof tumor to normal brain tissue uptake by (TI)-T-201 single-photon emission computed tomography. Single-voxel H-1-MRS was performed to measure the levels of metabolites in the tumors. Ki-67 LI was measured in the surgical specimens. RESULTS: All three gangliogliomas showed very high Tl-201 uptake on both early and delayed images. H-1-MRS demonstrated malignancy based on the high choline peak relative to the creatine and N-acetylaspartate peaks. Ki-67 LIwas less than 1% in two gangliogliomas and 3.5% in an anaplastic ganglioglioma. CONCLUSION: Both Tl-201 single-photon emission computed tomography and H-1-MRS indicated malignancy, whereas Ki-67 LI indicated low growth activity. Tl-201 single-photon emission computed tomography and H-1-MRS of ganglioglioma might be affected by metabolic characteristics other than growth activity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 17:05:35