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Titolo:
Radiofrequency catheter ablation of frequent monomorphic ventricular ectopic activity
Autore:
Seidl, K; Schumacher, B; Hauer, B; Jung, W; Drogemulle, A; Senges, J; Luderitz, B;
Indirizzi:
Herzzentrum Ludwigshafen, D-67063 Ludwigshafen, Germany Herzzentrum Ludwigshafen Ludwigshafen Germany D-67063 wigshafen, Germany Univ Bonn, Dept Med, D-5300 Bonn, Germany Univ Bonn Bonn Germany D-5300Univ Bonn, Dept Med, D-5300 Bonn, Germany
Titolo Testata:
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
fascicolo: 7, volume: 10, anno: 1999,
pagine: 924 - 934
SICI:
1045-3873(199907)10:7<924:RCAOFM>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
TACHYCARDIA; ARRHYTHMIAS;
Keywords:
catheter ablation; mapping;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Seidl, K Herzzentrum Ludwigshafen, Bremserstr 79, D-67063 Ludwigshafen, Germany Herzzentrum Ludwigshafen Bremserstr 79 Ludwigshafen Germany D-67063
Citazione:
K. Seidl et al., "Radiofrequency catheter ablation of frequent monomorphic ventricular ectopic activity", J CARD ELEC, 10(7), 1999, pp. 924-934

Abstract

Introduction: Frequent ventricular ectopic beats can result in severe symptoms and may even be incapacitating in some patients. Although radiofrequency catheter ablation is an effective and safe therapy for drug refractory idiopathic ventricular tachycardia, it has not been widely used in ventricular ectopy. The purpose of this study was: (1) to assess the potential role of catheter ablation in eliminating monomorphic ventricular ectopy in symptomatic patients regarding feasibility and safety and (2) to determine the usefulness of various mapping strategies. Methods and Results: Forty-one patients with symptomatic ventricular ectopic activity (right ventricular origin in 23 patients, left ventricular origin in 18 patients) were enrolled, The mean frequency of ventricular ectopicbeats was 1512 +/- 583/hour documented by Holter ECG monitoring. These patients had previously been unable to tolerate or had been unsuccessfully treated with a mean of 3 +/- 1 antiarrhythmic agents. The site of origin was mapped using earliest endocardial activation times, unipolar electrograms and pace mapping. Radiofrequency ablation was successful in 34 (83%) of 41 patients. Multivariate logistic regression analysis revealed pace mapping as the only independent predictor for a successful ablation site (P < 0.01). After a follow-up of 3 months, the overall success rate was 71%, The mean frequency of ventricular ectopic beats after successful ablation was 12 +/- 10 ventricular premature beat/hour, Conclusion: Radiofrequency catheter ablation is an effective and safe treatment for frequent symptomatic drug refractory monomorphic ventricular ectopic activity, Pace mapping predicts best successful ablation of ventricular ectopic beats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 08:33:13