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Titolo:
SSRIS AND HYPONATREMIA
Autore:
LANE RM;
Indirizzi:
PFIZER INC,PFIZER PHARMACEUT GRP,235 E 42ND ST NEW YORK NY 10017
Titolo Testata:
British journal of clinical practice
fascicolo: 3, volume: 51, anno: 1997,
pagine: 144 - 146
SICI:
0007-0947(1997)51:3<144:SAH>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIDIURETIC-HORMONE SECRETION; INAPPROPRIATE ANTI-DIURESIS; PSYCHOTROPIC-DRUGS; WATER-INTOXICATION; SERTRALINE THERAPY; DIURETIC HORMONE; TRANSIENT SIADH; HYPONATREMIA; FLUOXETINE; CARBAMAZEPINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
59
Recensione:
Indirizzi per estratti:
Citazione:
R.M. Lane, "SSRIS AND HYPONATREMIA", British journal of clinical practice, 51(3), 1997, pp. 144-146

Abstract

Increasing age, certain medications such as diuretics, disease processes such as malignant neoplasm and schizophrenia, and a history of hyponatraemia or polydipsia may predispose patients to the development ofhyponatraemia. In addition, certain psychotropic medications, including TCAs, MAOIs, carbamazepine, trazodone and neuroleptics, may predispose to hyponatraemia, yet a causative role for most has not been firmly established and the effect is most likely to be more idiosyncratic. The SSRIs have been associated with hyponatraemia in a small number ofcase reports. The mean age and sex of patients in reported cases is over 70 years and predominantly female, and patients were often receiving concomitant diuretic therapy, The frequency of hyponatraemia in elderly female patients receiving fluoxetine has been estimated to be as high as eight per 1000, The risk of developing hyponatraemia appears to be highest during the first few weeks of treatment, Because of the potential seriousness of hyponatraemia, if an elderly patient receivingan SSRI develops unexplained symptoms during the first few weeks of therapy, it is necessary to measure the serum sodium level.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 03:03:17