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Titolo:
Utility of the BTA stat test kit for bladder cancer screening
Autore:
Nasuti, JF; Gomella, LG; Ismial, M; Bibbo, M;
Indirizzi:
Thomas Jefferson Univ Hosp, Philadelphia, PA 19107 USA Thomas Jefferson Univ Hosp Philadelphia PA USA 19107 elphia, PA 19107 USA
Titolo Testata:
DIAGNOSTIC CYTOPATHOLOGY
fascicolo: 1, volume: 21, anno: 1999,
pagine: 27 - 29
SICI:
8755-1039(199907)21:1<27:UOTBST>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY CYTOLOGY; ACCURACY;
Keywords:
transitional-cell carcinoma; voided urine cytology; BTA stat test;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Nasuti, JF Hosp Univ Penn, Dept Pathol, 3400 Spruce St, Philadelphia, PA 19104 USA Hosp Univ Penn 3400 Spruce St Philadelphia PA USA 19104 104 USA
Citazione:
J.F. Nasuti et al., "Utility of the BTA stat test kit for bladder cancer screening", DIAGN CYTOP, 21(1), 1999, pp. 27-29

Abstract

Our study evaluated the BTA (bladder tumor antigen) stat test kit as a primary screening device for the detection of transitional-cell carcinoma (TCC) of the bladder; with direct comparison by voided urine cytology (VUC) on the sa,ne specimens. The unfixed voided urine of 100 patients with no history of bladder cancer who had signs and symptoms of dysuria, incontinence, and gross hematuria and microhematuria were tested using the one-step BTA stat test kit before processing via the cytospin technique for fluid cytological evaluation. The patients in the study were followed for up to 12 mo with repented urine cytological testing cystoscopy, and bladder biopsy when clinically indicated Nineteen cases tested positive, and 81 cases rested negative on the BTA stat test. VUC diagnosed three cases as unequivocally positive for TCC, 93 cases as negative, and four cases in which unqualified atypical urothelial cells were noted TCC was confirmed by cystoscopy and bladder biopsy in three of three cases diagnosed by VUC and in three of 19 cases that tested positive bl the BTA slat test. These findings resulted in an 84% false-positive rate for the BTA stat rest and no Salse-positive cases forVUC during the 12-mo follow-up period The results indicate that the sensitivity a,ld specificity of BTA stat test air comparable to those of VUC; however; owing to a relatively high false-positive rate, it can at hest act asan adjunct to urine cytological study for bladder cancer screening. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:17:58