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Titolo:
MRI-based brain volumetrics: emergence of a developmental brain science
Autore:
Caviness, VS; Lange, NT; Makris, N; Herbert, MR; Kennedy, DN;
Indirizzi:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Neurol, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 h Med, Dept Neurol, Boston, MA 02114 USA Harvard Univ, Sch Med, McLean Hosp, Dept Psychiat, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 osp, Dept Psychiat, Boston, MA 02114 USA Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Radiol, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 h Med, Dept Radiol, Boston, MA 02114 USA
Titolo Testata:
BRAIN & DEVELOPMENT
fascicolo: 5, volume: 21, anno: 1999,
pagine: 289 - 295
SICI:
0387-7604(199907)21:5<289:MBVEOA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSESSIVE-COMPULSIVE DISORDER; CEREBRAL-CORTEX; STRUCTURAL ABNORMALITIES; SCHIZOPHRENIC-PATIENTS; MORPHOMETRIC ANALYSIS; HUNTINGTONS-DISEASE; INFANTILE-AUTISM; HUMAN NEOCORTEX; SIZE; PARCELLATION;
Keywords:
volumetrics; MRI; cerebral cortex; human brain;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: Caviness, VS Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Neurol, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 eurol, Boston, MA 02114 USA
Citazione:
V.S. Caviness et al., "MRI-based brain volumetrics: emergence of a developmental brain science", BRAIN DEVEL, 21(5), 1999, pp. 289-295

Abstract

MRI-based brain volumetrics is an established methodology of great versatility and reliability with a broad range of potential applications in medicine and basic human brain science. We consider here, more theoretical implications of brain tissue volumes. Specifically, we suggest that volume is an evolutionarily and developmentally regulated fundamental property of tissue, in this instance the brain and its component structures. Within this framework (1), regularities in relative variation of volumes with respect to mean volume of a structure are viewed as systematic manifestations of the rules of histogenetic process (2), regularities in the relative strength of correlation of volumes of structures are suggested to reflect constraints which serve systematically the requirements of neural systems operation. Thesehypotheses, if supported by extensive observation, may guide the design ofapplications of MRI based volumetric analysis of the human brain. (C) 1999Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 18:10:09