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Titolo:
Schizoaffective disorder: Evidence for reversed cerebral asymmetry
Autore:
Reite, M; Teale, P; Rojas, DC; Sheeder, J; Arciniegas, D;
Indirizzi:
Univ Colorado, Hlth Sci Ctr, Biomagnet Imaging Lab, Dept Psychiat, Denver,CO 80262 USA Univ Colorado Denver CO USA 80262 Lab, Dept Psychiat, Denver,CO 80262 USA Denver VAMC, Mental Hlth Serv, Denver, CO USA Denver VAMC Denver CO USADenver VAMC, Mental Hlth Serv, Denver, CO USA
Titolo Testata:
BIOLOGICAL PSYCHIATRY
fascicolo: 1, volume: 46, anno: 1999,
pagine: 133 - 136
SICI:
0006-3223(19990701)46:1<133:SDEFRC>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOKED MAGNETIC-FIELDS; SOMATOSENSORY CORTEX; EXTENSIVE REORGANIZATION; SEX-DIFFERENCES; ADULT HUMANS; SCHIZOPHRENIA; PSYCHOSIS; LATERALIZATION; MAGNETOENCEPHALOGRAPHY; ABNORMALITIES;
Keywords:
somatosensory evoked fields; cerebral laterality; magnetoencephalography; psychoses; M20;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Reite, M Univ Colorado, Hlth Sci Ctr, Biomagnet Imaging Lab, Dept Psychiat, Box C268-68,4200 E 9th Ave, Denver, CO 80262 USA Univ Colorado Box C268-68,4200 E 9th Ave Denver CO USA 80262 USA
Citazione:
M. Reite et al., "Schizoaffective disorder: Evidence for reversed cerebral asymmetry", BIOL PSYCHI, 46(1), 1999, pp. 133-136

Abstract

Background: Schizoaffective disorder is one of the most severe of the affective psychoses, but its pathophysiology is poorly understood, Because cerebral lateralization may be disturbed in psychotic disorders generally, studies examining cerebral asymmetry may improve understanding of the neurobiology specific to schizoaffective disorder. This study examines cerebral lateralization in this patient population using magnetic source localization. Methods: We studied 16 subjects with schizoaffective disorder and 16 controls. Magnetic source localization was used to identify the location of the 20 msec latency somatosensory evoked field component (M20),Results: In control subjects, the source location was further anterior in the right hemisphere, The subjects with schizoaffective disorder were reverse lateralized,Conclusions: The findings of a reversed asymmetry of the M20 in patients with schizoaffective disorder suggest an anatomical shift in the placement of the post central gyrus in this disorder, compatible with a disorder of cerebral lateralization. Whether this finding converges or diverges with measurement of the M20 in other psychotic disorders will require further investigation (C) 1999 Society of Biological Psychiatry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 07:15:46