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Titolo:
Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices"
Autore:
Hoffman, RE; Boutros, NN; Berman, RM; Roessler, E; Belger, A; Krystal, JH; Charney, DS;
Indirizzi:
Yale Univ, Inst Psychiat, Sch Med, Dept Psychiat, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 , Dept Psychiat, New Haven, CT 06520 USA
Titolo Testata:
BIOLOGICAL PSYCHIATRY
fascicolo: 1, volume: 46, anno: 1999,
pagine: 130 - 132
SICI:
0006-3223(19990701)46:1<130:TMSOLT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Keywords:
auditory hallucinations; transcranial magnetic stimulation; schizophrenia; speech processing; cerebral cortex; psychosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Hoffman, RE Yale Univ, Inst Psychiat, Sch Med, Dept Psychiat, POB 208038, New Haven, CT 06520 USA Yale Univ POB 208038 New Haven CT USA 06520 aven, CT 06520 USA
Citazione:
R.E. Hoffman et al., "Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices"", BIOL PSYCHI, 46(1), 1999, pp. 130-132

Abstract

Background: Prior studies suggest that auditory hallucinations of "voices"arise from activation of speech perception areas of the cerebral cortex. Low frequency transcranial magnetic stimulation (TMS) can reduce cortical activation. Methods: We have studied three schizophrenic patients reporting persistentauditory hallucinations to determine if low frequency TMS could curtail these experiences. One hertz stimulation of left temporoparietal cortex was compared with sham stimulation using a double-blind crossover design. Results: All three patients demonstrated greater improvement in hallucination severity following active stimulation compared to sham stimulation. Twoof the three patients reported near total cessation of hallucinations for greater than or equal to 2 weeks. Conclusions: TMS may advance our understanding of the mechanism and treatment of auditory hallucinations. (C) 1999 Society of Biological Psychiatry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:50:53