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Titolo:
Changes in blood platelets exposed to UV-B radiation
Autore:
Bednarska, K; Wachowicz, B;
Indirizzi:
Univ Lodz, Dept Gen Biochem, PL-90237 Lodz, Poland Univ Lodz Lodz PolandPL-90237 , Dept Gen Biochem, PL-90237 Lodz, Poland
Titolo Testata:
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
fascicolo: 2-3, volume: 49, anno: 1999,
pagine: 187 - 191
SICI:
1011-1344(199904)49:2-3<187:CIBPET>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
ULTRAVIOLET; ACTIVATION;
Keywords:
UVB; blood platelets; lipid peroxidation; secretory processes; adenine nucleotides;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Bednarska, K Univ Lodz, Dept Gen Biochem, Banacha 12-16, PL-90237 Lodz, Poland Univ Lodz Banacha 12-16 Lodz Poland PL-90237 37 Lodz, Poland
Citazione:
K. Bednarska e B. Wachowicz, "Changes in blood platelets exposed to UV-B radiation", J PHOTOCH B, 49(2-3), 1999, pp. 187-191

Abstract

The effects of UV-B radiation (312 nm) on the pig-blood platelet secretoryprocess (platelet activation) and platelet lipid peroxidation have been studied. The responses of platelets to UV-B radiation are compared with the response of these cells to thrombin, which is a strong platelet agonist. Theobtained results show that exposure of blood platelets to UV-B radiation (1.2 mW/cm(2), 0.072-8.64 J/cm(2)) causes dose-dependent platelet Lipid peroxidation (measured as thiobarbituric acid reactive substances, TBARS) and release of adenine nucleotides and proteins from irradiated platelets. The dose-dependent release of platelet compounds from irradiated platelet does not correlate with the activity of platelet lactic dehydrogenase (marker of cell lysis) in the extracellular medium. It seems that UV-B radiation can partly activate platelets by stimulating the platelet secretory process and metabolism of arachidonate. (C) 1999 Elsevier Science S.A. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 09:18:19