Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Effect of initial periodontal therapy on the frequency of detecting Bacteroides forsythus, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans
Autore:
Takamatsu, N; Yano, K; He, T; Umeda, M; Ishikawa, I;
Indirizzi:
Tokyo,Med & Dent Univ, Fac Dent, Dept Periodontol, Bunkyo Ku, Tokyo 1135849 Tokyo Med & Dent Univ Tokyo Japan 1135849 ntol, Bunkyo Ku, Tokyo 1135849
Titolo Testata:
JOURNAL OF PERIODONTOLOGY
fascicolo: 6, volume: 70, anno: 1999,
pagine: 574 - 580
SICI:
0022-3492(199906)70:6<574:EOIPTO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOCALIZED JUVENILE PERIODONTITIS; ADULT PERIODONTITIS; ROOT DEBRIDEMENT; PROGRESSIVE PERIODONTITIS; SUBGINGIVAL PLAQUE; MOLAR TEETH; PATHOGENS; LESIONS; POCKETS; INTERMEDIUS;
Keywords:
DNA probes; Bacteroides forsythus; Porphyromonas gingivalis; Actinobacillus actinomycetemcomitans; periodontal diseases therapy; periodontal diseases microbiology; polymerase chain reaction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Yano, K Tokyoa,ed & Dent Univ, Fac Dent, Dept Periodontol, Bunkyo Ku, 1-5-45 Yushim Tokyo Med & Dent Univ 1-5-45 Yushima Tokyo Japan 1135849 5 Yushim
Citazione:
N. Takamatsu et al., "Effect of initial periodontal therapy on the frequency of detecting Bacteroides forsythus, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans", J PERIODONT, 70(6), 1999, pp. 574-580

Abstract

Background: Porphyromonas gingivalis, Bacteroides forsythus, and Actinobacillus actinomycetemcomitans have been described as periodontopathic bacteria, and their presence in subgingival pockets can lead to development of periodontal disease. Until now, clinical parameters have been used to evaluatethe effect of conventional periodontal treatment without microbiological parameters. The present study examined the microbiological effects of initial periodontal therapy using DNA probes and the polymerase chain reaction (PCR). Methods: Twenty-six, patients with periodontitis, 10 males and 16 females,were given instructions regarding oral hygiene, then thoroughly treated byconventional scaling and root planing. Bacterial samples were collected onpaper points from 4 sites per patient at baseline and after initial therapy (total: 104 sites). Clinical parameters including probing depth, attachment level, and bleeding on probing were also recorded for each site at baseline and after therapy. A DNA probe kit was used to monitor the frequency ofB. forsythus, P. gingivalis, and A. actinomycetemcomitans, the last of which was identified by PCR. Results: At baseline, B. forsythus was the bacterium most frequently detected. DNA probe analysis also showed that more than half of the sites were colonized by both B. forsythus and P. gingivalis. Initial therapy resulted in significant clinical improvement such as significant reduction in the frequency of B. forsythus and P. gingivalis detected using the DNA probe. A. actinomycetemcomitans was difficult to detect using the DNA probe, but PCR indicated that levels of A. actinomycetemcomitans did not significantly decrease. Conclusions: These results indicate that initial conventional therapy can eliminate P. forsythus and B. gingivalis, but not A. actinomycetemcomitans. When levels of these bacteria decreased to below-detectable levels, clinical improvement was significant. These results indicate that monitoring levels of these three periodontopathic bacteria may render periodontal therapy more effective and accurate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:15:23