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Titolo:
Clinical evaluation of Bio-Oss (R): a bovine-derived xenograft for the treatment of periodontal osseous defects in humans
Autore:
Richardson, CR; Mellonig, JT; Brunsvold, MA; McDonnell, HT; Cochran, DL;
Indirizzi:
Univ Texas, Hlth Sci Ctr, Dept Periodont, San Antonio, TX 78284 USA Univ Texas San Antonio TX USA 78284 Periodont, San Antonio, TX 78284 USA Wilford Hall USAF Med Ctr, MRDT, Dept Periodont, Lackland AFB, TX 78236 USA Wilford Hall USAF Med Ctr Lackland AFB TX USA 78236 and AFB, TX 78236 USA
Titolo Testata:
JOURNAL OF CLINICAL PERIODONTOLOGY
fascicolo: 7, volume: 26, anno: 1999,
pagine: 421 - 428
SICI:
0303-6979(199907)26:7<421:CEOB(A>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
FREEZE-DRIED BONE; ATTACHMENT APPARATUS FORMATION; HISTOLOGIC EVALUATION; POROUS HYDROXYLAPATITE; INTRABONY DEFECTS; BIO-OSS; ALLOGRAFT; RESPONSES; IMPLANTS; HYDROXYAPATITE;
Keywords:
Bio-Oss (R); intrabony defect; DFDBA; periodontal surgery; regeneration; bone grafts; re-entry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Mellonig, JT UnivTXexas, Hlth Sci Ctr, Dept Periodont, 7703 Floyd Curl Dr,San Antonio, Univ Texas 7703 Floyd Curl Dr San Antonio TX USA 78284 tonio,
Citazione:
C.R. Richardson et al., "Clinical evaluation of Bio-Oss (R): a bovine-derived xenograft for the treatment of periodontal osseous defects in humans", J CLIN PER, 26(7), 1999, pp. 421-428

Abstract

The purpose of this study was to compare the bovine derived xenograft (BDX) Bio-Oss(R) to demineralized freeze dried bone allograft (DFDBA) in human intrabony defects. 17 healthy patients with no systemic disease with moderate-severe periodontitis (7 males, 10 females; aged 34-67), were treated. Surgically, defects were included only if the intraosseous defect depth was >3.0 mm. Final selection included 30 defects. The sites were randomly assigned treatment with DFDBA or BDX. Soft tissue and osseous defect measurementswere taken the day of surgery and 6 months post-operatively at re-entry. Average baseline PD, GAL, and surgical defect depth for the DFBBA group werenot statistically different from the BDX group. No adverse healing response occurred. The re suits showed a statistically significant improvement in PD and AL for both materials at 6 months in 26 defects (4 defects did not respond to therapy). Soft tissue measurements for the DFDBA group included PD reduction of 2.0+/-1.3 mm, and AL gain of 2.6+/-1.6 mm, while the BDX group showed a PD reduction of 3.0+/-1.7 mm, and AL gain of 3.6+/-1.8 mm. Osseous measurements showed bone fill of 2.4 mm (46.8%,) for the DFDBA group and 3.0 mm (55.8%) for the BDX group. Defect resolution was 59.4% for the DFDBA group and 77.6% for the BDX group. Statistical analysis revealed there was no statistical difference be tween the 2 materials in all measurements.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:40:06