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Titolo:
The calibration and validation of a phase-modulated near-infrared cerebraloximeter
Autore:
Levy, WJ; Carpenter, J; Fairman, RM; Golden, MA; Zager, E;
Indirizzi:
Univ Penn, Sch Med, Dept Anesthesia, Philadelphia, PA 19104 USA Univ PennPhiladelphia PA USA 19104 nesthesia, Philadelphia, PA 19104 USA Univ Penn, Sch Med, Dept Surg, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 Dept Surg, Philadelphia, PA 19104 USA Univ Penn, Sch Med, Dept Neurosurg, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 Neurosurg, Philadelphia, PA 19104 USA
Titolo Testata:
JOURNAL OF CLINICAL MONITORING AND COMPUTING
fascicolo: 2, volume: 15, anno: 1999,
pagine: 103 - 108
SICI:
1387-1307(199902)15:2<103:TCAVOA>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXYGEN-SATURATION; SPECTROSCOPY;
Keywords:
monitoring : near infrared spectroscopy; O-2 saturation, cerebral; brain : ischemia; surgery : carotid artery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Levy, WJ Hosp Univ Penn, 3400 Spruce St, Philadelphia, PA 19104 USA Hosp Univ Penn 3400 Spruce St Philadelphia PA USA 19104 19104 USA
Citazione:
W.J. Levy et al., "The calibration and validation of a phase-modulated near-infrared cerebraloximeter", J CLIN M C, 15(2), 1999, pp. 103-108

Abstract

Objective. This study was undertaken to compare the cerebral oxygenation measured by an experimental phase-modulated near-infrared (NIR) spectroscopysystem with capillary saturation estimated from jugular venous oxygen saturation. Methods. Jugular venous catheters were placed in 30 patients undergoing carotid endarterectomy and 194 measurements of venous oxygen saturation were obtained intra operatively. Simultaneous measurement of optical pathlength at 754, 785, and 816 nm was performed using a phase-modulated near-infrared spectroscopy system. Optical calibration was performed using both an optical bench and a scattering mold. Hemoglobin saturation was calculated from NIR measurements using equations derived from diffusion theory. Capillary saturation was calculated from the arterial and venous saturations. Results. Jugular venous saturations ranged from 41 to 92%. When calibrated using the optical bench, the NIR estimates of hemoglobin saturation deviatedfrom estimated capillary values by an average of 2.6% bias and 4.3% deviation. No systematic bias was noted. NIR values derived from mold calibrationwere less accurate and precise (4.6% bias and 6.9% deviation. ) Use of the initial venous sample as an in vivocalibration improved the accuracy of themold calibration but did not alter the performance of the bench calibration. Conclusions. Under the conditions tested, an experimental phase-modulated near-infrared spectroscopy system calibrated using an optical bench agreed with capillary saturation estimated from jugular venous samples. Further work is necessary to demonstrate valid performance of the system under other conditions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 12:33:21