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Titolo:
Current theories on the causes of inflammatory bowel disease
Autore:
Papadakis, KA; Targan, SR;
Indirizzi:
Cedars Sinai Med Ctr, Ctr Inflammatory Bowel Dis, Los Angeles, CA 90048 USA Cedars Sinai Med Ctr Los Angeles CA USA 90048 , Los Angeles, CA 90048 USA UnivSAalif Los Angeles, Sch Med, Div Gastroenterol, Los Angeles, CA 90024 U Univ Calif Los Angeles Los Angeles CA USA 90024 , Los Angeles, CA 90024 U
Titolo Testata:
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
fascicolo: 2, volume: 28, anno: 1999,
pagine: 283 -
SICI:
0889-8553(199906)28:2<283:CTOTCO>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES; CD4(+) T-CELLS; CHRONIC INTESTINAL INFLAMMATION; COLITIC C3H/HEJBIR MICE; COLON EPITHELIAL-CELLS; NECROSIS-FACTOR-ALPHA; RECEPTOR MUTANT MICE; HLA CLASS-II; CROHNS-DISEASE; ULCERATIVE-COLITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
96
Recensione:
Indirizzi per estratti:
Indirizzo: Targan, SR Cedarsverlyi Med Ctr, Ctr Inflammatory Bowel Dis, Davis Bldg,D-4063,8700 Be Cedars Sinai Med Ctr Davis Bldg,D-4063,8700 Beverly Blvd Los Angeles CA USA 90048
Citazione:
K.A. Papadakis e S.R. Targan, "Current theories on the causes of inflammatory bowel disease", GASTRO CLIN, 28(2), 1999, pp. 283

Abstract

The understanding of the pathogenesis of Crohn's disease and ulcerative colitis has greatly expanded over the last decade. The combination of abnormalities in the immune system, the contribution of nonimmune cells in the intestinal mucosa, a variety of genetic risk determinants, and random environmental factors may all be necessary to induce what clinically presents as inflammatory bowel disease. It is likely that several agents can initiate an immune response that in the intestinal microenvironment and the genetic background of the patient finally leads to pathology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 16:59:40