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Titolo:
Laparoscopic prophylactic oophorectomy in women with inherited risk of ovarian cancer
Autore:
Morice, P; Pautier, P; Mercier, S; Spatz, A; Lhomme, C; Duvillard, P; Gerbaulet, A; Castaigne, D;
Indirizzi:
Inst Gustave Roussy, Dept Gynecol Surg, F-94805 Villejuif, France Inst Gustave Roussy Villejuif France F-94805 , F-94805 Villejuif, France
Titolo Testata:
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
fascicolo: 3, volume: 20, anno: 1999,
pagine: 202 - 204
SICI:
0392-2936(1999)20:3<202:LPOIWW>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
FAMILY HISTORY; FOLLOW-UP; BRCA1; CARCINOMA; MUTATIONS;
Keywords:
inherited ovarian cancer; laparoscopy; adnexectomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Morice, P InstVillejuif,oussy, Dept Gynecol Surg, 39 Rue Camille Desmoulins, F-94805 Inst Gustave Roussy 39 Rue Camille Desmoulins Villejuif France F-94805
Citazione:
P. Morice et al., "Laparoscopic prophylactic oophorectomy in women with inherited risk of ovarian cancer", EUR J GYN O, 20(3), 1999, pp. 202-204

Abstract

The aim of this study was to specify the surgical procedure most adapted for prophylactic laparoscopic oophorectomy in patients with an inherited risk of ovarian cancer. This prospective study was based on a series of 27 patients who underwent prophylactic bilateral laparoscopic oophorectomy between September 1995 and January 1998. Nine patients underwent an oophorectomy (33%) and 18 patients an adnexectomy (67%). The laparoscopic procedure was converted into a laparotomy in one patient in whom an ovarian adenocarcinoma was detected during the surgical procedure. During final histologic examination of the ovaries, 23 patients were found to have benign atypical histologic alterations, one patient had an ovarian adenocarcinoma and only threepatients (11%) had normal ovaries. In women with an inherited risk of ovarian cancer, during the laparoscopicprocedure for prophylactic oophorectomy, the abdomino-pelvic cavity shouldbe thoroughly explored with peritoneal cytology and systematic peritoneal biopsies. The laparoscopic procedure could be converted into a laparotomy if an ovarian cancer is discovered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:39:28