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Titolo:
IMPORTANCE OF FLOW METABOLISM STUDIES IN PREDICTING LATE RECOVERY OF FUNCTION FOLLOWING REPERFUSION IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION/
Autore:
MAES A; MORTELMANS L; NUYTS J; BORMANS G; HERREGODS MC; BIJNENS B; VANDEWERF F;
Indirizzi:
UZ GASTHUISBERG,DEPT NUCL MED,HERESTR 49 B-3000 LOUVAIN BELGIUM UZ GASTHUISBERG,DEPT NUCL MED B-3000 LOUVAIN BELGIUM UZ GASTHUISBERG,DEPT CARDIOL B-3000 LOUVAIN BELGIUM
Titolo Testata:
European heart journal
fascicolo: 6, volume: 18, anno: 1997,
pagine: 954 - 962
SICI:
0195-668X(1997)18:6<954:IOFMSI>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; REGIONAL BLOOD-FLOW; OXIDATIVE-METABOLISM; GLUCOSE-UTILIZATION; N-13 AMMONIA; WALL-MOTION; PERFUSION; DEOXYGLUCOSE; THROMBOLYSIS; TISSUE;
Keywords:
MYOCARDIAL INFARCTION; THROMBOLYSIS; POSITRON EMISSION TOMOGRAPHY; VIABILITY; STUNNING; FUNCTIONAL RECOVERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
A. Maes et al., "IMPORTANCE OF FLOW METABOLISM STUDIES IN PREDICTING LATE RECOVERY OF FUNCTION FOLLOWING REPERFUSION IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION/", European heart journal, 18(6), 1997, pp. 954-962

Abstract

Aims Positron emission tomographic imaging is known to be a reliable indicator of viable myocardium in chronic heart disease. Its value in acute myocardial infarction has not been studied extensively. Methods and results Sixty-two patients receiving thrombolytic therapy were studied. Myocardial tissue flow and metabolism were measured at 5 days and 3 months. Recovery of left ventricular function was investigated with echocardiography or radionuclide ventriculography. In eight patients, normal flow was found in the infarct area at 5 days with no significant changes in flow, metabolism or function over the next 3 months. In54 patients. impaired regional myocardial blood flow in the infarct zone was observed at 5 days. In 39 patients, there was a matching positron emission tomographic pattern, while in 15 the pattern was mismatched. None of the patients with a TIMI flow grade <3 revealed recovery of left ventricular function. In seven out of 11 patients with TIMI 3 flow and a mismatching pattern, additional angioplasty was performed with functional improvement in six. Conclusions Recovery of ventricular function is exclusively found in patients with a TIMI flow grade 3. Patients with a positron emission tomographic mismatching pattern revealfunctional recovery only after subsequent angioplasty.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:27:04