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Titolo:
Idiopathic parkinsonism with superimposed manganese exposure: Utility of positron emission tomography
Autore:
Kim, YH; Kim, JW; Ito, KG; Lim, HS; Cheong, HK; Kim, JY; Shin, YC; Kim, KS; Moon, YH;
Indirizzi:
Korea Ind Safety Corp, Ind Hlth Res Inst, Incheon 403711, South Korea Korea Ind Safety Corp Incheon South Korea 403711 eon 403711, South Korea Dong A Univ Hosp, Dept Neurol, Pusan, South Korea Dong A Univ Hosp PusanSouth Korea osp, Dept Neurol, Pusan, South Korea Natl Inst Longev Sci, Dept Biofunct Res, Obu, Japan Natl Inst Longev Sci Obu Japan ongev Sci, Dept Biofunct Res, Obu, Japan Dongguk Univ, Coll Med, Dept Prevent Med, Pohang, South Korea Dongguk Univ Pohang South Korea , Dept Prevent Med, Pohang, South Korea
Titolo Testata:
NEUROTOXICOLOGY
fascicolo: 2-3, volume: 20, anno: 1999,
pagine: 249 - 252
SICI:
0161-813X(199904/06)20:2-3<249:IPWSME>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
F-18 DOPA-PET; PARENTERAL-NUTRITION; BASAL GANGLIA; DISEASE; ENCEPHALOPATHY; INTOXICATION;
Keywords:
18F-6-fluorodopa; high signal intensities; magnetic resonance image; manganism; idiopathic parkinsonism; manganese exposure; positron emission tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, YH Korea403711,fety Corp, Ind Res Inst, Bupyeong Ku, 34-6 Kusan Dong,Incheon Korea Ind Safety Corp 34-6 Kusan Dong Incheon South Korea 403711
Citazione:
Y.H. Kim et al., "Idiopathic parkinsonism with superimposed manganese exposure: Utility of positron emission tomography", NEUROTOXICO, 20(2-3), 1999, pp. 249-252

Abstract

It is difficult to distinguish manganism from idiopathic parkinsonism by clinical signs only. Case history and examination: A 48-year-old welder for over 10 years complained of masked lace right side (arm and leg) resting tremor, and bradykinesia for over one year. Magnetic resonance imaging (MRI) findings showed symmetrical high signal intensities in the globus pallidus on T1 weighted image. These intensities disappeared almost completely six months after cessation of exposure. F-18-6-fluorodopa (F-18-dopa) positron emission tomography (PET) findings showed reduced F-18-dopa uptake in the left putamen, findings which appear in idiopathic parkinsonism. A PET study is necessary to distinguish manganism from idiopathic parkinsonism, especially in a working environment with elevated Mn concentrations, such as welding. (C) 1999 Intox Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 08:39:56