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Titolo:
Interpretive reproducibility of stress Tc-99m sestamibi tomographic myocardial perfusion imaging
Autore:
Golub, RJ; Ahlberg, AW; McClellan, JR; Herman, SD; Travin, MI; Mather, JF; Aitken, PW; Baron, JI; Heller, GV;
Indirizzi:
Hartford Hosp, Div Cardiol, Nucl Cardiol Lab, Hartford, CT 06102 USA Hartford Hosp Hartford CT USA 06102 l Cardiol Lab, Hartford, CT 06102 USA Brown912iv, Sch Med, Roger Williams Med Ctr, Div Cardiol, Providence, RI 02 Brown Univ Providence RI USA 02912 ed Ctr, Div Cardiol, Providence, RI 02 Brown Univ, Mem Hosp Rhode Isl, Div Cardiol, Pawtucket, RI 02860 USA BrownUniv Pawtucket RI USA 02860 l, Div Cardiol, Pawtucket, RI 02860 USA Hosp Univ Penn, Div Cardiol, Philadelphia, PA 19104 USA Hosp Univ Penn Philadelphia PA USA 19104 diol, Philadelphia, PA 19104 USA Univ Connecticut, Sch Med, Dept Med, Farmington, CT USA Univ Connecticut Farmington CT USA Sch Med, Dept Med, Farmington, CT USA Univ Connecticut, Sch Med, Dept Nucl Med, Farmington, CT USA Univ Connecticut Farmington CT USA ed, Dept Nucl Med, Farmington, CT USA
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 3, volume: 6, anno: 1999,
pagine: 257 - 269
SICI:
1071-3581(199905/06)6:3<257:IROSTS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; METHOXY ISOBUTYL ISONITRILE; OBSERVER AGREEMENT; NUCLEAR CARDIOLOGY; MULTICENTER TRIAL; CLINICAL-DATA; TL-201; PLANAR; VARIABILITY; CRITERIA;
Keywords:
tomographic imaging; interpretive reproducibility; intraobserver agreement; interobserver agreement;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Heller, GV Hartfordord,p, Div Cardiol, Nucl Cardiol Lab, 80 Seymour St,POB5037, Hartf Hartford Hosp 80 Seymour St,POB 5037 Hartford CT USA 06102 artf
Citazione:
R.J. Golub et al., "Interpretive reproducibility of stress Tc-99m sestamibi tomographic myocardial perfusion imaging", J NUCL CARD, 6(3), 1999, pp. 257-269

Abstract

Background: Observer variability has been shown with interpretation of planar thallium-201 images. The interpretive reproducibility of technetium-99msestamibi tomographic imaging is unknown. This study evaluated the interpretive reproducibility of interpretable Tc-99m sestamibi tomographic images among nuclear cardiologists with a wide range of training and experience. Methods: Three experienced readers (EX) and 3 less-experienced readers (LEX) interpreted 138 exercise and rest Tc-99m sestamibi tomographic images (101 were abnormal in patients with coronary artery disease [CAD], 37 were normal inpatients with <5% likelihood of CAD) twice in random sequence without clinical data. Images of good to excellent quality were randomly selectedfrom a database at 2 nuclear cardiology laboratories. Intraobserver and interobserver agreement for global, left anterior descending (LAD) territory,non-LAD first (normal/abnormal) and second (normal/fixed/reversible) order, and defect extent (normal/single-vessel CAD/multi-vessel CAD) were assessed with percent agreement and Cohen's kappa (kappa) statistic. Results: With regard to intraobserver agreement, first and second order ranged from 87% to 94% and 80% to 90% for global, 82% to 96% and 78% to 95% for LAD, and 88% to 91% and 80% to 90% for non-LAD, respectively. Defect extent ranged from 75% to 90%. There were no differences between EX and LEX for global and non-LAD first and second order, LAD first order, and defect extent. LAD second order was 93% for EX compared with 88% (P = .015) for LEX,With regard to interobserver agreement, first and second order ranged from73% to 89% and 64% to 85% for global, 73% to 93% and 69% to 91% for LAD, and 76% to 88% and 68% to 84% for non-LAD; respectively. Defect extent ranged from 61% to 82%. Global first and second order ranged from 85% to 87% and78% to 82% for EX compared with 73% to 84% and 64% to 79% for LEX. LAD first and second order ranged from 89% to 91% and 88% to 89% for EX compared with 73% to 91% and 69% to 70% for LEX. Non-LAD first and second order ranged from 82% to 86% and 76% to 77% for EX compared with 76% to 86% and 68% to81% for LEX. Defect extent ranged from 69% to 75% for EX compared with 59%to 77% for LEX. Conclusions: There is moderate to excellent interpretive reproducibility with stress Tc-99m sestamibi SPECT imaging among nuclear cardiologists with a wide range of training and experience.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 10:18:02