Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The role of surgery in pediatric gliomas
Autore:
Pollack, IF;
Indirizzi:
Univurgh,sburgh, Dept Neurosurg, Childrens Hosp Pittsburgh, Sch Med, Pittsb Univ Pittsburgh Pittsburgh PA USA 15213 Hosp Pittsburgh, Sch Med, Pittsb
Titolo Testata:
JOURNAL OF NEURO-ONCOLOGY
fascicolo: 3, volume: 42, anno: 1999,
pagine: 271 - 288
SICI:
0167-594X(199905)42:3<271:TROSIP>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHILDRENS-CANCER-GROUP; CHOROID-PLEXUS CARCINOMA; LOW-GRADE GLIOMAS; PRIMITIVE NEUROECTODERMAL TUMORS; PROSPECTIVE RANDOMIZED TRIAL; CENTRAL-NERVOUS-SYSTEM; BRAIN-STEM GLIOMAS; INTRACRANIAL EPENDYMOMA; CEREBRAL HEMISPHERES; RADIATION-THERAPY;
Keywords:
brain tumor; childhood; glioma; medulloblastoma; surgery; therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Pollack, IF Univthittsburgh, Dept Neurosurg, Childrens Hosp Pittsburgh, Sch Med, 3705 5 Univ Pittsburgh 3705 5th Ave Pittsburgh PA USA 15213 d, 3705 5
Citazione:
I.F. Pollack, "The role of surgery in pediatric gliomas", J NEURO-ONC, 42(3), 1999, pp. 271-288

Abstract

Pediatric glial tumors differ from adult gliomas in several ways that are of major therapeutic importance. First, the value of extensive tumor resection, which is controversial for malignant intrinsic brain tumors in adults,has been confirmed for a variety of childhood brain tumors, such as supratentorial high-grade and low-grade gliomas and infratentorial low-grade gliomas, ependymomas, and some medulloblastomas. Second, chemotherapy has been found to be effective in improving overall outcome in several childhood brain tumors, such as medulloblastoma and supratentorial high-grade glioma, but has yet to be proven to have a major benefit for adult tumors. In addition, chemotherapy is increasingly used to delay or avoid radiotherapy in young children with high-grade and incompletely resected low-grade tumors to avoid the morbidity of irradiation on the developing nervous system. Third, the prognosis for histologically similar tumors is often more favorable in children than adults. The present chapter will highlight the unique featuresof childhood glial tumors, discuss general principles in the clinical presentation, diagnostic evaluation, and treatment of these tumors, and then focus on the surgical management and outcome of the more common types of tumors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:07:47