Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Outcome of schizophrenia in relation to brain abnormalities
Autore:
Staal, WG; Pol, HEH; Kahn, RS;
Indirizzi:
Univ Utrecht Hosp, Dept Psychiat, NL-3584 CX Utrecht, Netherlands Univ Utrecht Hosp Utrecht Netherlands NL-3584 CX CX Utrecht, Netherlands
Titolo Testata:
SCHIZOPHRENIA BULLETIN
fascicolo: 2, volume: 25, anno: 1999,
pagine: 337 - 348
SICI:
0586-7614(1999)25:2<337:OOSIRT>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL VENTRICULAR ENLARGEMENT; FOLLOW-UP; TEMPORAL-LOBE; NEGATIVE SYMPTOMS; FIRST-EPISODE; 3RD VENTRICLE; STRUCTURAL ABNORMALITIES; COGNITIVE IMPAIRMENT; PREFRONTAL CORTEX; PLANUM TEMPORALE;
Keywords:
outcome; course; neuroimaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
81
Recensione:
Indirizzi per estratti:
Citazione:
W.G. Staal et al., "Outcome of schizophrenia in relation to brain abnormalities", SCHIZO BULL, 25(2), 1999, pp. 337-348

Abstract

This article reviews the 21 studies that investigated possible relationships between structural brain abnormalities and outcome in schizophrenia. Fifteen studies used computer tomography to visualize brain morphology, In these studies, images were obtained of the ventricles but not of specific brain regions. The remaining six studies used magnetic resonance imaging, examining possible relationships between outcome, ventricular size, and specificbrain regions. One out of two studies found relationships between brain structure and outcome, The data suggest that the extent of ventricular enlargement in patients with schizophrenia may be related to outcome. No clear relationship between outcome and changes in specific brain regions was found. Apart from considerations about the methodology of measuring different brain regions, the procedure used to measure outcome is important, Outcome, asit is assessed at various points during the coarse of illness, may be variable and seems to fluctuate during the first 10 to 15 years of disease. Significantly, to date no studies relating outcome to brain structure have used patient samples with a duration of illness longer than 15 years.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 07:22:05