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Titolo:
Characteristic values of MR examinations of cerebral perfusion with high spatial and temporal resolution
Autore:
Klose, U; Nagele, T; Friese, S; Bitzer, M;
Indirizzi:
Univ Tubingen, Abt Neuroradiol, Tubingen, Germany Univ Tubingen TubingenGermany ngen, Abt Neuroradiol, Tubingen, Germany UnivGermanyen, Sekt Expt Kernspinresonanz Zentralen Nervernsyst, Tubingen,Univ Tubingen Tubingen Germany esonanz Zentralen Nervernsyst, Tubingen,
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 5, volume: 170, anno: 1999,
pagine: 474 - 481
SICI:
0936-6652(199905)170:5<474:CVOMEO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
GER
Soggetto:
BLOOD-VOLUME; CEREBROVASCULAR-DISEASE; CONTRAST AGENT; SUSCEPTIBILITY; BRAIN; FLOW; NMR; STROKE; TIME;
Keywords:
magnetic resonance imaging; brain; echo-planar-imaging; perfusion; evaluation parameter;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Klose, U UnivSeylerTubingen, Abt Neuroradiol, Sekt Expt Kernspinresonanz ZNS, Hoppe Univ Klin Tubingen Hoppe Seyler Str 3 Tubingen Germany D-72076 e
Citazione:
U. Klose et al., "Characteristic values of MR examinations of cerebral perfusion with high spatial and temporal resolution", ROFO-F RONT, 170(5), 1999, pp. 474-481

Abstract

Purpose: Different parameters for the evaluation of perfusion studies withdynamic MR-measurements after the administration of paramagnetic contrast agent were compared. Method: An echo planar imaging (EPI) sequence was developed that allows dynamic multi-slice data acquisition. Evaluations of the measurements were performed by calculating parameter maps. Phenomenologicalquantities such as maximal signal reduction and time to peak as well as derived quantities such as approximations of the regional cerebral blood volume were used as parameters. Patients with a low grade astrocytoma, with an acute cerebral infarction and with stenoses of the carotid arteries were examined. Results: On comparison of the derived parameters with the phenomenological parameters no major differences were found in qualitative comparisons of the parameter maps. The comparison of relative parameter values in selected regions within the datasets of 20 patients show a high correspondence between phenomenological and derived parameter values. Conclusions: UsingEPI measurement techniques with high temporal resolution, parameter maps of simple values like maximal signal reduction and time-to-peak are sufficient to visualize relative differences of perfusion within the selected slices. However, the calculation of relative rCBV and rCBF values might be helpful for the detailed characterization of signal courses in selected regions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:12:44