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Titolo:
Effects of scatter subtraction on detection and quantitation in hepatic SPECT
Autore:
de Vries, DJ; King, MA; Soares, EJ; Tsui, BMW; Metz, CE;
Indirizzi:
Univ Massachusetts, Sch Med, Dept Nucl Med, Worcester, MA USA Univ Massachusetts Worcester MA USA ed, Dept Nucl Med, Worcester, MA USA Coll Holy Cross, Dept Math, Worcester, MA 01610 USA Coll Holy Cross Worcester MA USA 01610 Dept Math, Worcester, MA 01610 USA Univ N Carolina, Dept Biomed Engn, Chapel Hill, NC USA Univ N Carolina Chapel Hill NC USA Dept Biomed Engn, Chapel Hill, NC USA Univ N Carolina, Dept Radiol, Chapel Hill, NC USA Univ N Carolina Chapel Hill NC USA ina, Dept Radiol, Chapel Hill, NC USA Univ Chicago, Med Ctr, Dept Radiol, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 Ctr, Dept Radiol, Chicago, IL 60637 USA
Titolo Testata:
JOURNAL OF NUCLEAR MEDICINE
fascicolo: 6, volume: 40, anno: 1999,
pagine: 1011 - 1023
SICI:
0161-5505(199906)40:6<1011:EOSSOD>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; ENERGY-WEIGHTED ACQUISITION; IMAGING TECHNIQUES; LESION DETECTION; ROC ANALYSIS; COMPENSATION; NOISE; OBSERVER; PHOTONS; QUALITY;
Keywords:
lesion detection; receiver operating characteristic analysis; scatter correction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: de Vries, DJ Brigham & Womens Hosp, Dept Radiol, 75 Francis St, Boston, MA02115 USA Brigham & Womens Hosp 75 Francis St Boston MA USA 02115 5 USA
Citazione:
D.J. de Vries et al., "Effects of scatter subtraction on detection and quantitation in hepatic SPECT", J NUCL MED, 40(6), 1999, pp. 1011-1023

Abstract

The purpose of this investigation was to examine the effects of subtractive scatter compensation methods on lesion detection and quantitation. Methods: Receiver operating characteristic (ROC) methodology was used to measure human observer detection accuracy for tumors in the liver using synthetic images. Furthermore, ROC results were compared with mathematical models for detection and activity quantitation to examine (a) the potential for predicting human performance and (b) the relationship between the detection and quantitation tasks. Images with both low and high amounts of scatter were compared with the ideal case of images of primary photons only (i.e., perfectscatter rejection) and with images corrected by subtracting a scatter image estimated by the dual photopeak window method. Results: With low contrasttumors in a low count background, the results showed that scatter subtraction improved quantitation but did not produce statistically significant increases in detection accuracy. However, primary images did produce some statistically significant improvements in detection accuracy when compared withuncorrected images, particularly for high levels of scatter. Conclusion: Although scatter subtraction methods may provide improved activity quantitation, they may not significantly improve detection for liver SPECT The results imply that significant improvement in detection accuracy for the conditions tested may depend on the development of gamma cameras with better scatter rejection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 18:58:04