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Titolo:
Fel d 1 and Can f 1 in settled dust and airborne Fel d 1 in allergen avoidance day-care centres for atopic children in relation to number of pet-owners, ventilation and general cleaning
Autore:
Wickman, M; Egmar, AC; Emenius, G; Almqvist, C; Berglind, N; Larsson, P; Van Hage-Hamsten, M;
Indirizzi:
Karolinska Hosp, Dept Environm Hlth, S-17176 Stockholm, Sweden Karolinska Hosp Stockholm Sweden S-17176 Hlth, S-17176 Stockholm, Sweden Karolinska Inst, Sachs Childrens Hosp, Stockholm, Sweden Karolinska Inst Stockholm Sweden achs Childrens Hosp, Stockholm, Sweden Karolinska Inst, Inst Environm Med, S-10401 Stockholm, Sweden Karolinska Inst Stockholm Sweden S-10401 Med, S-10401 Stockholm, Sweden Astrid,Lindgren Hosp Children, Div Childrens & Womens Hlth, Karolinska Inst Astrid Lindgren Hosp Children Stockholm Sweden ns Hlth, Karolinska Inst Natl Inst Working Life, Solna, Sweden Natl Inst Working Life Solna Sweden tl Inst Working Life, Solna, Sweden Karolinska Hosp & Inst, Dept Clin Immunol, Stockholm, Sweden Karolinska Hosp & Inst Stockholm Sweden Clin Immunol, Stockholm, Sweden
Titolo Testata:
CLINICAL AND EXPERIMENTAL ALLERGY
fascicolo: 5, volume: 29, anno: 1999,
pagine: 626 - 632
SICI:
0954-7894(199905)29:5<626:FD1ACF>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAT ALLERGEN; DOG CAN-F-1; ASTHMA; EXPOSURE; SENSITIZATION; ENVIRONMENTS; DEPOSITION; REDUCTION; CHILDHOOD; SYMPTOMS;
Keywords:
allergen; Can f 1; environment; Fel d 1; preschool; transfer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Wickman, M Karolinskaolm,p, Dept Environm Hlth, Norrbacka Bldg,Level 3, S-17176 Stockh Karolinska Hosp Norrbacka Bldg,Level 3 Stockholm Sweden S-17176
Citazione:
M. Wickman et al., "Fel d 1 and Can f 1 in settled dust and airborne Fel d 1 in allergen avoidance day-care centres for atopic children in relation to number of pet-owners, ventilation and general cleaning", CLIN EXP AL, 29(5), 1999, pp. 626-632

Abstract

Background Special day-care centres fur atopic children have been established in Sweden. Objective To study concentrations of cat (Fel d 1) and dog (Can f 1) allergens in settled dust and airborne cat allergen in day-care centres in relation to pet ownership among children and staff, ventilation and general cleaning. Methods Twelve allergen avoidance day-care centres and 23 conventional day-care centres were included in the study. Settled dust was collected and analysed with ELISA. Airborne cat allergen levels were measured in eight allergen avoidance and seven conventional centres with a personal air sampler and analysed with an amplified ELISA. Air change rate per hour (ACH) was measured. A questionnaire which focused on keeping of cat and dog among staff and children and frequency of general cleaning was used. Results In the allergen avoidance day-care centres neither children nor staff reported ownership of cats or dogs, compared with 21/22 of the conventional centres in which children and staff kept furred animals. Fel d 1 and Can f 1 were found in settled dust in all day-care centres. In the allergen avoidance compared with the conventional centres the concentrations of Fel d 1 and Can f 1 were lower, Fel d 1: median 0.64 mu g/g vs 5.45 mu g/g and Can f 1: 0.39 mu g/g vs 2.51, both P < 0.001, and airborne Fel d I was alsolower in the allergen avoidance centres compared with the control centres,1.51 ng/m(3) vs 15.8 n,/m(3), P = 0.002. A correlation was found between airborne and settled Fel d I, r(s)=0.75, P<0.001. Furthermore, a correlationwas found between increased ACH and decreased levels of Fel d 1 in the airin the day-care centres with no cat-owners, r(s) = - 0.86, P = 0.007, No relation was found between levels of cat or dog allergen and amount of general cleaning. Conclusion Not keeping pets seems to reduce children's exposure to pet-allergen in their working environment. Additionally, appropriate ventilation seems to reduce Fel d 1 in the air in day-care centres.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 05:42:53