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Titolo:
Differential immune system changes with acute and persistent stress for optimists vs pessimists
Autore:
Cohen, F; Kearney, KA; Zegans, LS; Kemeny, ME; Neuhaus, JM; Stites, DP;
Indirizzi:
Univ Calif San Francisco, Sch Med, Hlth Psychol Program, Dept Psychiat, San Univ Calif San Francisco San Francisco CA USA 94143 m, Dept Psychiat, San Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA Univ CalifLos Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA 90024 USA Univ Calif Los Angeles Los Angeles CA USA 90024 Los Angeles, CA 90024 USA Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 Univ Calif San Francisco San Francisco CA USA 94143 n Francisco, CA 94143 Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
BRAIN BEHAVIOR AND IMMUNITY
fascicolo: 2, volume: 13, anno: 1999,
pagine: 155 - 174
SICI:
0889-1591(199906)13:2<155:DISCWA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
KILLER-CELL-ACTIVITY; GENERALIZED OUTCOME EXPECTANCIES; LIFE ORIENTATION TEST; DISPOSITIONAL OPTIMISM; PHENOTYPICALLY DISTINCT; NEGATIVE AFFECTIVITY; MEDICAL-STUDENTS; SOCIAL SUPPORT; AIDS; MODULATION;
Keywords:
stress; chronic stress; optimism; personality; lymphocyte subsets; NK cell cytotoxicity; psychoneuroimmunology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Cohen, F Univ3Calif San Francisco, Sch Med, Hlth Psychol Program, Dept Psychiat, 333 Univ Calif San Francisco 3333 Calif St,Suite 465 San Francisco CA USA 94143
Citazione:
F. Cohen et al., "Differential immune system changes with acute and persistent stress for optimists vs pessimists", BRAIN BEH, 13(2), 1999, pp. 155-174

Abstract

This study investigated whether acute and persistent stressors and life change events were followed by changes in immune status, and whether dispositional optimism moderated these relationships. Thirty-nine healthy women ages 18-45 were followed prospectively for 3 months, with weekly assessment ofacute and persistent stressors and monthly assessment of life events and immune parameters (NK cell cytotoxicity, and CD4 and CD8 T cell subsets). The study used an autoregressive linear model to examine how weekly appraisedacute and persistent stress levels were associated with immune parameters in the subsequent week. Analyses revealed that the immune outcomes were differentially affected by acute and persistent stressors. Further, the association between acute stress and subsequent immune parameters was buffered byan optimistic perspective. However, when stress persisted at high levels, optimists showed more subsequent immune decrements than pessimists. (C) 1999 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/06/20 alle ore 02:31:50