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Titolo:
Pathogenic diversity of Escherichia coli and the emergence of 'exotic' islands in the gene stream
Autore:
Dozois, CM; Curtiss, R;
Indirizzi:
Washington Univ, Dept Biol, St Louis, MO 63130 USA Washington Univ St Louis MO USA 63130 , Dept Biol, St Louis, MO 63130 USA
Titolo Testata:
VETERINARY RESEARCH
fascicolo: 2-3, volume: 30, anno: 1999,
pagine: 157 - 179
SICI:
0928-4249(199903/06)30:2-3<157:PDOECA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSFER-RNA GENES; URINARY-TRACT INFECTION; SHIGELLA-FLEXNERI 2A; IN-VIVO EXPRESSION; K54 CAPSULAR POLYSACCHARIDE; ATTACHING-EFFACING LESIONS; ENTEROCYTE EFFACEMENT LEE; HOST EPITHELIAL-CELLS; YERSINIA-PESTIS; VIRULENCE FACTORS;
Keywords:
Escherichia coli; pathogenicity island; horizontal gene transfer; adaptation;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
180
Recensione:
Indirizzi per estratti:
Indirizzo: Curtiss, R Washington130iv, Dept Biol, Campus Box 1137,1 Brookings Dr, St Louis, MO 63 Washington Univ Campus Box 1137,1 Brookings Dr St Louis MO USA63130
Citazione:
C.M. Dozois e R. Curtiss, "Pathogenic diversity of Escherichia coli and the emergence of 'exotic' islands in the gene stream", VET RES, 30(2-3), 1999, pp. 157-179

Abstract

Escherichia coli is a highly adaptive bacterial species that is both a member of the commensal intestinal flora and a versatile pathogen associated with numerous types of intestinal and systemic infections in humans and other animals. The spectrum of diseases caused by E. coli is due to the acquisition of specific virulence genes harbored on plasmids, bacteriophages, or within distinct DNA segments termed pathogenicity islands (PAIs) that are absent from the genomes of commensal E. coli strains. PAIs are likely to havebeen transferred horizontally and may have integrated into the E. coli chromosome through bacteriophage or plasmid integration or transposition. The contribution of intergenic inheritance to the adaptation and evolution of E. coli, types of PAIs associated with different groups of pathogenic E. coli and approaches to identify unique sequence islands (USIs), some of which might confer pathogenicity, in E. coli and other bacteria are presented. (C) Inra/Elsevier, Paris.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 00:00:28