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Titolo:
New techniques in stereotaxic surgery and anesthesia in the mouse
Autore:
Messier, C; Emond, S; Ethier, K;
Indirizzi:
Univ Ottawa, Sch Psychol, Ottawa, ON K1N 6N5, Canada Univ Ottawa Ottawa ON Canada K1N 6N5 Psychol, Ottawa, ON K1N 6N5, Canada
Titolo Testata:
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
fascicolo: 2, volume: 63, anno: 1999,
pagine: 313 - 318
SICI:
0091-3057(199906)63:2<313:NTISSA>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
PENTOBARBITAL SLEEPING TIME; MICE; ISOFLURANE; RATS; METHOXYFLURANE; RODENTS; ACETAMINOPHEN; HALOTHANE; XYLAZINE; ANIMALS;
Keywords:
acetaminophen; cannula; isoflurane; methoxyflurane; mouse; sodium pentobarbital; stereotaxic instrument; surgery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Messier, C Univ Ottawa, Sch Psychol, Room 215, Ottawa, ON K1N 6N5, Canada Univ Ottawa Room 215 Ottawa ON Canada K1N 6N5 N K1N 6N5, Canada
Citazione:
C. Messier et al., "New techniques in stereotaxic surgery and anesthesia in the mouse", PHARM BIO B, 63(2), 1999, pp. 313-318

Abstract

Mice are used in increasing numbers in neuroscience research. This increase is linked to the availability of numerous pure genetic lines and the advent of transgenic animals. Many neuroscience techniques can be used in the mouse with success, including stereotaxic placement of cannulae and electrodes. With the recent publication of a mouse brain atlas by Franklin and Paxinos and improvements in surgical procedures for the mouse, stereotaxic surgery in mice can be performed routinely and with accuracy. In the present article, we describe techniques and apparatuses for the surgical implantationof cannulae in the mouse brain. We also present new developments in anesthesia, pain management, and postoperative care that improve survival and recover) times of mice. Using these new techniques, we have gained shorter training time for students, lower mortality rates following surgery, and faster recovery. (C) 1999 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 06:34:57