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Titolo:
Effects of modified pellicles on Candida biofilm formation on acrylic surfaces
Autore:
Nikawa, H; Nishimura, H; Hamada, T; Yamashiro, H; Samaranayake, LP;
Indirizzi:
Hiroshimaanniv, Sch Dent, Dept Prosthet Dent, Minami Ku, Hiroshima 734, Jap Hiroshima Univ Hiroshima Japan 734 t Dent, Minami Ku, Hiroshima 734, Jap Univngong Kong, Prince Philip Dent Hosp, Oral Biol Unit, Hong Kong, Hong Ko Univ Hong Kong Hong Kong Hong Kong , Oral Biol Unit, Hong Kong, Hong Ko
Titolo Testata:
MYCOSES
fascicolo: 1-2, volume: 42, anno: 1999,
pagine: 37 - 40
SICI:
0933-7407(199904)42:1-2<37:EOMPOC>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALBICANS GERM TUBES; HUMAN-FIBRINOGEN; INVITRO BINDING; ADHERENCE; SALIVA; SERUM; ADHESION; PROTEIN; FIBRONECTIN; RECEPTORS;
Keywords:
Candida albicans; Candida glabrata; Candida tropicalis; biofilm formation; mucin; fibronectin; saliva; serum;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Nikawa, H Hiroshimashima, Sch Dent, Dept Prosthet Dent, Minami Ku, 1-2-3 Kasumi, Hiro Hiroshima Univ 1-2-3 Kasumi Hiroshima Japan 734 -3 Kasumi, Hiro
Citazione:
H. Nikawa et al., "Effects of modified pellicles on Candida biofilm formation on acrylic surfaces", MYCOSES, 42(1-2), 1999, pp. 37-40

Abstract

The role of saliva or serum proteins, such as mucin, fibronectin (FN) and mannan-binding protein, on Candida biofilm formation was investigated. Supplementation of saliva with FN had no significant effect on biofilm formation. In contrast, biofilm formation on either mucin-coated or FN-coatcd acrylic surfaces was significantly less than that of the control. These results suggest that salivary mucin or FN alone does not facilitate biofilm formation of Candida. Supplementation of serum with FN increased biofilm formationof C. glabrata compared with the control. Pretreatment of serum with anti-FN monoclonal antibody significantly reduced biofilm formation, as did pretreatment of serum with anti-mannan-binding protein monoclonal antibody or Con-A. Therefore, Candida biofilm formation on acrylic surfaces appears to be a complex phenomenon involving a multiplicity of proteins operating intraorally.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 06:59:33