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Titolo:
Pulmonary function in children affected by juvenile spondyloarthropathy
Autore:
Camiciottoli, G; Trapani, S; Ermini, M; Falcini, F; Pistolesi, M;
Indirizzi:
Univ Florence, Dept Clin Pathophysiol, Resp Unit, Florence, Italy Univ Florence Florence Italy n Pathophysiol, Resp Unit, Florence, Italy Univ Florence, Dept Pediat, Rheumatol Unit, Florence, Italy Univ FlorenceFlorence Italy pt Pediat, Rheumatol Unit, Florence, Italy
Titolo Testata:
JOURNAL OF RHEUMATOLOGY
fascicolo: 6, volume: 26, anno: 1999,
pagine: 1382 - 1386
SICI:
0315-162X(199906)26:6<1382:PFICAB>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANKYLOSING-SPONDYLITIS; LUNG-FUNCTION; AGED 4; DISEASE;
Keywords:
spondyloarthropathy; childhood; pulmonary function tests;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Trapani, S Aorence,Hosp, Dept Pediat, Rheumatol Unit, Via Luca Giordano 13, I-50132 Fl A Meyer Hosp Via Luca Giordano 13 Florence Italy I-50132 32 Fl
Citazione:
G. Camiciottoli et al., "Pulmonary function in children affected by juvenile spondyloarthropathy", J RHEUMATOL, 26(6), 1999, pp. 1382-1386

Abstract

Objective, Pleuropulmonary involvement in adult spondyloarthropathy (SpA) has been thoroughly investigated. SpA is usually detected by conventional radiology as fibrosis of the upper lobes in about 30% of asymptomatic patients. Pulmonary function tests (PFT) reveal decreased vital capacity and total lung capacity, as well as increased residual volume. Juvenile SpA (JSpA) is a rare clinical condition, and no extensive investigations have been carried out on pulmonary involvement in JSpA. We studied prevalence and features of PFT alterations in patients with JSpA over a 2 year followup and analyzed the relationship between PFT and disease duration, disease activity, and chest and spine mobility. Methods. Eighteen patients with JSpA, with no clinical signs of lung disease and normal chest radiographs, underwent PFT - static and dynamic volumes, diffusing capacity for carbon monoxide (DLCO), at enrollment (TO), at 12 months (T1), and at 24 months later (T2). Disease activity was defined at each investigation by clinical and hematological data. Results. Significant functional lung impairment was detected in 33% of patients (reduced forced vital capacity in 22% and DLCO in 11%). No significant change in the prevalence and features of PFT alterations was detected at T1 and T2; no relationship was found between PFT and duration, activity, and clinical scores of the disease. Conclusion. Thirty-three percent of JSpA patients without clinical symptoms and no radiological findings of lung involvement show PFT alterations, mainly characterized by a restrictive pattern. No progression or modificationin PFT developed over 2 years. No correlation was found between PFT and disease duration, activity, and clinical scores.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 14:16:01