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Titolo:
Critical evaluation of medical, statistical, and occupational data sourcesin the Kola Peninsula of Russia pertinent to reproductive health studies
Autore:
Odland, JO; Tchachtchine, VP; Bykov, V; Fiskebeck, PE; Lund, E; Thomassen, Y; Nieboer, E;
Indirizzi:
Univ Tromso, Inst Community Med, N-9037 Tromso, Norway Univ Tromso Tromso Norway N-9037 st Community Med, N-9037 Tromso, Norway Kola Res Lab Occupat Hlth, Kirovsk, Russia Kola Res Lab Occupat Hlth Kirovsk Russia Occupat Hlth, Kirovsk, Russia Dept Environm Affairs, Off Finnmark Cty Governor, Vadso, Norway Dept Environm Affairs Vadso Norway Finnmark Cty Governor, Vadso, Norway Natl Inst Occupat Hlth, Oslo, Norway Natl Inst Occupat Hlth Oslo NorwayNatl Inst Occupat Hlth, Oslo, Norway McMaster Univ, Dept Biochem, Hamilton, ON, Canada McMaster Univ Hamilton ON Canada niv, Dept Biochem, Hamilton, ON, Canada McMaster Univ, Occupat Hlth Program, Hamilton, ON, Canada McMaster Univ Hamilton ON Canada upat Hlth Program, Hamilton, ON, Canada
Titolo Testata:
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
fascicolo: 3, volume: 72, anno: 1999,
pagine: 151 - 160
SICI:
0340-0131(199905)72:3<151:CEOMSA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
NICKEL; TOXICITY; MALFORMATIONS; EXPOSURE;
Keywords:
Russia; epidemiology; nickel workers; reproduction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Odland, JO Univ Tromso, Inst Community Med, N-9037 Tromso, Norway Univ Tromso Tromso Norway N-9037 y Med, N-9037 Tromso, Norway
Citazione:
J.O. Odland et al., "Critical evaluation of medical, statistical, and occupational data sourcesin the Kola Peninsula of Russia pertinent to reproductive health studies", INT A OCCUP, 72(3), 1999, pp. 151-160

Abstract

Background: The feasibility study described herein was prompted by a report in 1992 of possible reproductive and developmental health concerns among female workers in a Russian nickel refinery. Objective: The primary goal was to ascertain whether medical, statistical, and occupational data bases could be accessed for information about the pregnancy histories, occupationalhistories, and life-style factors of the women affected. Methods: The project was facilitated by construction of a registry of all births in three towns with a nickel refinery and verification of its contents against patients' records obtained from hospital delivery and gynecology departments and community polyclinics. Municipal Registration Board, Regional Health Statistics Board, and nickel company records were also reviewed. Results: Reproductive/developmental outcome information and workplace histories were acceptable. Sample-size calculations indicated that a cohort or cross-sectional study would be amenable and suitable for the detection of an excess risk for spontaneous abortion with adequate statistical significance and power. Suchinvestigations would need to be supplemented by workplace environmental/biological monitoring assessments for evaluation of exposure to occupational hazardous factors and a worker's questionnaire to obtain information about life-style factors. A case-control design is recommended for the study of congenital defects. Conclusions: A well-designed, comprehensive epidemiologystudy is technically feasible because of the availability of a favorable pool of study subjects, reproductive/developmental outcome data, informationto control for major confounders, and suitable occupational records.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 07:06:52