Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Reduced heart rate variability following repair of tetralogy of Fallot
Autore:
McLeod, KA; Hillis, WS; Houston, AB; Wilson, N; Trainer, A; Neilson, J; Doig, WB;
Indirizzi:
Royal Hosp Sick Children, Dept Cardiol, Glasgow G3 8SJ, Lanark, Scotland Royal Hosp Sick Children Glasgow Lanark Scotland G3 8SJ Lanark, Scotland Univ Glasgow, Robertson Ctr Biostat, Glasgow, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland Biostat, Glasgow, Lanark, Scotland Royal Infirm, Dept Med Phys, Edinburgh EH3 9HB, Midlothian, Scotland RoyalInfirm Edinburgh Midlothian Scotland EH3 9HB , Midlothian, Scotland
Titolo Testata:
HEART
fascicolo: 6, volume: 81, anno: 1999,
pagine: 656 - 660
SICI:
1355-6037(199906)81:6<656:RHRVFR>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIAC PARASYMPATHETIC ACTIVITY; VENTRICULAR ARRHYTHMIA; MYOCARDIAL-INFARCTION; SUDDEN-DEATH; AUTONOMIC FUNCTION; DISEASE; FIBRILLATION; MECHANISMS; FREQUENCY; MORTALITY;
Keywords:
tetralogy of Fallot; heart rate variability; right ventricular function; congenital heart disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: McLeod, KA Royal Hosp Sick Children, Dept Cardiol, Glasgow G3 8SJ, Lanark,Scotland Royal Hosp Sick Children Glasgow Lanark Scotland G3 8SJ otland
Citazione:
K.A. McLeod et al., "Reduced heart rate variability following repair of tetralogy of Fallot", HEART, 81(6), 1999, pp. 656-660

Abstract

Objective-To examine autonomic function as assessed by heart rate variability in patients 10 or more years after repair of tetralogy of Fallot, and to relate this to cardiac structure, function, and electrocardiographic indices. Methods-Heart rate variability was measured by standard time domain techniques on a 24 hour Holter ECG in 28 patients, aged 12 to 34 years (mean 19.5), who had undergone repair of tetralogy of Fallot at least 10 years previously. Echocardiography was performed to assess left ventricular size and function, right ventricular size and pressure, and any proximal pulmonary arterial stenosis. Right ventricular function was evaluated by radionuclide scan. QRS duration, QT interval, and QT dispersion were measured on a standard 12 lead EGG. Measurements of heart rate variability were compared with values from 28 age matched healthy controls (mean age 19.9 years). Interrelations between variables were assessed using Pearson correlation coefficientsand stepwise regression analysis. Results-Heart rate variability was reduced, compared with values for age matched normal controls, in 12 of the 28 patients. Reduced heart rate variability was associated with increased age, increased right ventricular size and pressure, and widening of the QRS complex. Conclusions-Reduced heart rate variability is a feature following repair of tetralogy of Fallot. It is associated with increasing age, impaired rightventricular haemodynamics, and widening of the QRS complex. Under these circumstances, reduced heart rate variability may be a marker for deteriorating right ventricular function. Increased QRS duration has been identified as a risk factor for sudden death following repair of tetralogy of Fallot, and impaired cardiac autonomic control may be one of the mechanisms involved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 11:21:18