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Titolo:
Cardioprotection of red wine: Role of polyphenolic antioxidants
Autore:
Das, DK; Sato, M; Ray, PS; Maulik, G; Engelman, RM; Bertelli, AAE; Bertelli, A;
Indirizzi:
Univ Connecticut, Sch Med, Farmington, CT 06030 USA Univ Connecticut Farmington CT USA 06030 ch Med, Farmington, CT 06030 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA HarvardUniv Boston MA USA 02115 a Farber Canc Inst, Boston, MA 02115 USA Baystate Med Ctr, Springfield, MA USA Baystate Med Ctr Springfield MA USA aystate Med Ctr, Springfield, MA USA Univ Milan, Inst Anat, Milan, Italy Univ Milan Milan ItalyUniv Milan, Inst Anat, Milan, Italy Univ Milan, Dept Pharmacol, Milan, Italy Univ Milan Milan ItalyUniv Milan, Dept Pharmacol, Milan, Italy
Titolo Testata:
DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH
fascicolo: 2-3, volume: 25, anno: 1999,
pagine: 115 - 120
SICI:
0378-6501(1999)25:2-3<115:CORWRO>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISCHEMIA-REPERFUSION; DENSITY-LIPOPROTEIN; LIPID-PEROXIDATION; FREE-RADICALS; HEART; CONSUMPTION; INJURY; PLASMA; RISK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Das, DK Univ Connecticut, Sch Med, Farmington, CT 06030 USA Univ Connecticut Farmington CT USA 06030 Farmington, CT 06030 USA
Citazione:
D.K. Das et al., "Cardioprotection of red wine: Role of polyphenolic antioxidants", DRUG EXP CL, 25(2-3), 1999, pp. 115-120

Abstract

Epidemiological studies suggest that the consumption of wine, particularlyof red wine, reduces the incidence of mortality and morbidity from coronary hear? disease. This has given rise to what is now popularly termed the "French paradox". The cardioprotective effect has been attributed to antioxidants present in the polyphenol fraction of red wine. Grapes contain a variety of antioxidants, including resveratrol, catechin, epicatechin and proanthocyanidins. Of these resveratrol is present mainly in grape skin while proanthocyanidin is present in the seeds. In this report, we provide evidence that red wine extract as well as resveratrol and proanthocyanidins are equally effective in reducing myocardial ischemic reperfusion injury which suggests that these red wine polyphenolic antioxidants play a crucial role in cardioprotection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 13:06:08