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Titolo:
Bone marrow transplantation for paroxysmal nocturnal haemoglobinuria
Autore:
Bemba, M; Guardiola, P; Garderet, L; Devergie, A; Ribaud, P; Esperou, H; Noguera, MH; Gluckman, E; Socie, G;
Indirizzi:
Hop St Louis, Serv Greffe Moelle, F-75475 Paris 10, France Hop St Louis Paris France 10 erv Greffe Moelle, F-75475 Paris 10, France Hop St Louis, Cent Hematol Lab, F-75475 Paris, France Hop St Louis ParisFrance F-75475 ent Hematol Lab, F-75475 Paris, France
Titolo Testata:
BRITISH JOURNAL OF HAEMATOLOGY
fascicolo: 2, volume: 105, anno: 1999,
pagine: 366 - 368
SICI:
0007-1048(199905)105:2<366:BMTFPN>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOGLOBINURIA;
Keywords:
paroxysmal nocturnal haemoglobinuria; bone marrow transplantation; long-term follow-up;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
9
Recensione:
Indirizzi per estratti:
Indirizzo: Socie, G Hop St Louis, Serv Greffe Moelle, 1 Ave Claude Vellefaux, F-75475Paris 10, Hop St Louis 1 Ave Claude Vellefaux Paris France 10 75 Paris 10,
Citazione:
M. Bemba et al., "Bone marrow transplantation for paroxysmal nocturnal haemoglobinuria", BR J HAEM, 105(2), 1999, pp. 366-368

Abstract

Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of the haemopoietic stem cells for which the only curative treatment is bone marrow transplantation. There are few reports on the use of allogeneic transplantation for PNH, and nearly all of them include only a few patients. Between September 1978 and December 1997, 16 patients underwent marrow transplantation for PNH at the Hospital Saint Louis. The 5-year survival rate for the 16 patients was 58 +/- 13%, Two factors, an absolute neutrophil count >1.0 x 10(9)/l and haemoglobin level >9 g/dl at transplant, were found tobe statistically associated with a better outcome.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 11:32:50