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Titolo:
Severe lactic acidosis reveals an allergy to cow milk.
Autore:
Rizk, C; Valdes, L; de Baulny, HO; Saudubray, JM; Olivier, C;
Indirizzi:
Hop Louis Mourier, Serv Pediat, F-92700 Colombes, France Hop Louis Mourier Colombes France F-92700 diat, F-92700 Colombes, France Hop Robert Debre, Ctr Invest Clin, F-75019 Paris, France Hop Robert DebreParis France F-75019 Invest Clin, F-75019 Paris, France Hop Necker Enfants Malad, Serv Genet, F-75015 Paris, France Hop Necker Enfants Malad Paris France F-75015 net, F-75015 Paris, France
Titolo Testata:
ARCHIVES DE PEDIATRIE
fascicolo: 4, volume: 6, anno: 1999,
pagine: 427 - 429
SICI:
0929-693X(199904)6:4<427:SLARAA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
FRE
Keywords:
acidosis, lactic; milk proteins; hypersensitivity; infant nutrition disorders;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Rizk, C Hopceouis Mourier, Serv Pediat, 178 Rue Renouillers, F-92700 Colombes, Fran Hop Louis Mourier 178 Rue Renouillers Colombes France F-92700 ran
Citazione:
C. Rizk et al., "Severe lactic acidosis reveals an allergy to cow milk.", ARCH PED, 6(4), 1999, pp. 427-429

Abstract

The age of discovery and initial symptoms of cow milk allergy can vary. Lactic acidosis is exceptionally associated to this allergy. Case report. - A 32-day-old girl war admitted for a severe;malaise with metabolic acidosis and hyperlactacidemia, There were no neonatal or family problems; breastfeeding was stopped on the 25th day. Fever was noted on the 29th day and her mother reported behavior anomalies followed by a severe malaise with unconsciousness between the 29th and 32nd day. At admission, the infant showed a severe neurological distress, hypotonia and lethargy. Infection and neurological imaging were normal A compensated metabolic acidosis with hyperlactacidemia (5.96 mmol/L) was noted. There was no argument for esophageal reflux nor vagal hypertony; mitochondrial cytopathy was also excluded After a 24 hours fast, the clinical state gradually improved and normalized at h48. The infant was discharged with a milk protein hydrolysate formula. Her mother attempted to reintroduce cow milk on the 59th and 64th day, but this was immediately followed by allergic manifestations which supported the diagnosis of cow cow milk allergy. Conclusion, - Neurological distress and hyperlactacidemia exceptionally reveal this type of intolerance. The mechanism of hyperlactacidemia remains unclear; it is possibly the consequence of severe changes of the intestinal mucosa, an exclusive glycolytic tissue. (C) 1999 Elsevier, Paris.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 20:06:59