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Titolo:
Maternal separation: hypothalamic-preoptic area and hippocampal Calbindin-D-28K and calretinin in male and female infantile rats
Autore:
Lephart, ED; Watson, MA;
Indirizzi:
Brigham Young Univ, Dept Zool, Div Cell Biol, Provo, UT 84602 USA Brigham Young Univ Provo UT USA 84602 Div Cell Biol, Provo, UT 84602 USA
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 1, volume: 267, anno: 1999,
pagine: 41 - 44
SICI:
0304-3940(19990521)267:1<41:MSHAAH>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING FACTOR; MEDIAL BASAL HYPOTHALAMUS; CALCIUM; EXPRESSION; ESTROGEN; NEURONS; PROTEIN; GENE;
Keywords:
maternal separation; Calbindin-D-28K; calretinin; hypothalamus; hippocampus; rat; western analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Lephart, ED Brigham Young Univ, Dept Zool, Div Cell Biol, Provo, UT 84602 USA Brigham Young Univ Provo UT USA 84602 ol, Provo, UT 84602 USA
Citazione:
E.D. Lephart e M.A. Watson, "Maternal separation: hypothalamic-preoptic area and hippocampal Calbindin-D-28K and calretinin in male and female infantile rats", NEUROSCI L, 267(1), 1999, pp. 41-44

Abstract

Calcium-binding proteins (CaPs) potentially play important roles in neurogenesis and neuronal survival. Calbindin-D-28K (CALB) and calretinin (CALRET) in the media! basal hypothalamic (and preoptic area) (MBH) and hippocampus (HIPPO) from control and maternally separated male and female infantile rats were examined by Western analysis. Significantly greater levels of the CaPs in the MBH vs, the HIPPO may suggest enhanced or decreased neuroprotection, respectively, during the stress hyporesponsive period (SHRP). Male infantile rats separated from their mother's from postnatal day 2-10 displayed significant changes in CALB and CALRET for the MBH (decrease) and HIPP (increase) brain sites suggesting possible modified (negative feedback) mechanism(s) in HPA dysfunction observed during postnatal life. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 20:35:45