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Titolo:
Distribution of prolactin-releasing peptide-immunoreactive neurons in the rat hypothalamus
Autore:
Yamakawa, K; Kudo, K; Kanba, S; Arita, J;
Indirizzi:
Yamanashi Med Univ, Dept Physiol, Yamanashi, Japan Yamanashi Med Univ Yamanashi Japan Univ, Dept Physiol, Yamanashi, Japan Yamanashi Med Univ, Dept Psychiat, Yamanashi, Japan Yamanashi Med Univ Yamanashi Japan niv, Dept Psychiat, Yamanashi, Japan
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 2, volume: 267, anno: 1999,
pagine: 113 - 116
SICI:
0304-3940(19990528)267:2<113:DOPPNI>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARAVENTRICULAR NUCLEUS; MEDIAN-EMINENCE; PREOPTIC AREA; SECRETION; PITUITARY; HORMONE; BRAIN;
Keywords:
prolactin-releasing peptide; hypothalamic dorsomedial nucleus; immunocytochemistry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Arita, J Yamanashi Med Univ, Dept Physiol, Yamanashi, Japan Yamanashi Med Univ Yamanashi Japan t Physiol, Yamanashi, Japan
Citazione:
K. Yamakawa et al., "Distribution of prolactin-releasing peptide-immunoreactive neurons in the rat hypothalamus", NEUROSCI L, 267(2), 1999, pp. 113-116

Abstract

A newly identified hypothalamic peptide whose specific receptors are present in the anterior pituitary gland is a selective and potent stimulator of prolactin secretion and is therefore termed prolactin-releasing peptide (PRP). We investigated the distribution of PRP-containing neurons in the hypothalamus of female rats by immunocytochemical techniques. Immunocytochemistry using a specific antibody raised to PRP revealed that PRP-immunoreactive perikarya were located in the posteroventral part of the dorsomedial nucleus of the hypothalamus. PRP-immunoreactive nerve terminals were present in high concentrations in a region ventral to the bed nucleus of the stria terminalis, but scarcely observed in the external layer of the median eminence in which well known hypothalamic hormones such as growth hormone-releasing hormone and somatostatin were abundantly detected. Th is specific distribution in the hypothalamus suggests a novel route of the hypophysiotropic action of PRP. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 23:51:37