Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Incidence and risk factors of benign creatine phosphokinase elevations in chronic psychiatric patients
Autore:
Terao, T; Matsuda, S; Kojima, H; Okuno, K; Hori, H; Kaku, A; Ueda, N; Etoh, A;
Indirizzi:
Univkuokapat & Environm Hlth, Dept Psychiat, Yahatanishi Ku, Kitakyushu, Fu Univ Occupat & Environm Hlth Kitakyushu Fukuoka Japan 8078555 akyushu, Fu Univ,Occupat & Environm Hlth, Dept Community Hlth & Prevent Med, Kitakyushu Univ Occupat & Environm Hlth Kitakyushu Fukuoka Japan 8078555 Kitakyushu Komine Etoh Hosp, Kitakyushu, Fukuoka, Japan Komine Etoh Hosp Kitakyushu Fukuoka Japan sp, Kitakyushu, Fukuoka, Japan
Titolo Testata:
NEUROPSYCHOBIOLOGY
fascicolo: 4, volume: 39, anno: 1999,
pagine: 173 - 180
SICI:
0302-282X(1999)39:4<173:IARFOB>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Keywords:
creatine phosphokinase; chronic psychiatric inpatients; neuroleptics; physical activity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Terao, T Univkuokapat & Environm Hlth, Dept Psychiat, Yahatanishi Ku, Kitakyushu, Fu Univ Occupat & Environm Hlth Kitakyushu Fukuoka Japan 8078555 Fu
Citazione:
T. Terao et al., "Incidence and risk factors of benign creatine phosphokinase elevations in chronic psychiatric patients", NEUROPSYCHB, 39(4), 1999, pp. 173-180

Abstract

There have been few studies focusing on the creatine phosphokinase (CPK) elevations in chronic psychiatric patients. The survey was conducted prospectively to investigate the incidence and risk factors of CPK elevations in chronic psychiatric patients during a 2-year follow-up period. Sixteen of 32(50%) patients had maximums of more than 230 U/I (upper limit of our normal range) and 7 (22%) patients had maximums of more than 500 U/I. Surprisingly, 4 (13%) patients had maximums of more than 1,000 U/I after exercises such as swimming and walking. Nonetheless, none of the 16 patients with the CPK elevations developed severe conditions such as rhabdomyolysis despite anabsence of therapeutic intervention, and their CPK elevations were proven to be benign. According to the path analysis, usual physical activity and neuroleptic doses seemed to underlie CPK elevations directly. The present findings suggest that not a few chronic psychiatric inpatients may have at least one CPK elevation per 2 years. Patients engaging in more physical activity or receiving higher neuroleptic doses are at greater risk of developingsuch CPK elevations. However, most of these increases are benign, and it is not considered necessary to treat them.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 22:39:59