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Titolo:
Analysis of vaginal cell populations during experimental vaginal candidiasis
Autore:
Fidel, PL; Luo, W; Steele, C; Chabain, J; Baker, M; Wormley, F;
Indirizzi:
Louisianaans,te Univ, Med Ctr, Dept Microbiol Immunol & Parasitol, New Orle Louisiana State Univ New Orleans LA USA 70112 munol & Parasitol, New Orle
Titolo Testata:
INFECTION AND IMMUNITY
fascicolo: 6, volume: 67, anno: 1999,
pagine: 3135 - 3140
SICI:
0019-9567(199906)67:6<3135:AOVCPD>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELLS; MOUSE VAGINA; PHENOTYPICALLY DISTINCT; CHLAMYDIA-TRACHOMATIS; PROTECTIVE IMMUNITY; MURINE CANDIDIASIS; MEDIATED-IMMUNITY; MUCOSAL IMMUNITY; GENITAL-TRACT; ALBICANS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Fidel, PL Louisianadidote Univ, Med Ctr, Dept Microbiol Immunol & Parasitol, 1901 Per Louisiana State Univ 1901 Perdido St New Orleans LA USA 70112 er
Citazione:
P.L. Fidel et al., "Analysis of vaginal cell populations during experimental vaginal candidiasis", INFEC IMMUN, 67(6), 1999, pp. 3135-3140

Abstract

Studies with an estrogen-dependent murine model of vaginal candidiasis suggest that local cell-mediated immunity (CMI) is more important than systemic CMI for protection against vaginitis. The present study, however, showed that, compared to uninfected mice, little to no change in the percentage ortypes of vaginal T cells occurred during a primary vaginal infection or during a secondary vaginal infection where partial protection was observed. Furthermore, depletion of polymorphonuclear leukocytes (PMN) had no effect on infection in the presence or absence of pseudoestrus. These results indicate a lack of demonstrable effects by systemic CMI or PMN against vaginitisand suggest that if local T cells are important, they are functioning without showing significant increases in numbers within the vaginal mucosa during infection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 04:25:47