Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Coefficient of variation of interspike intervals greater than 0.5. How andwhen?
Autore:
Feng, JF; Brown, D;
Indirizzi:
Babraham Inst, Computat Neurosci Lab, Cambridge CB2 4AT, England Babraham Inst Cambridge England CB2 4AT Lab, Cambridge CB2 4AT, England
Titolo Testata:
BIOLOGICAL CYBERNETICS
fascicolo: 5, volume: 80, anno: 1999,
pagine: 291 - 297
SICI:
0340-1200(199905)80:5<291:COVOII>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNAPTIC TRANSMISSION; REVERSAL POTENTIALS; NEOCORTICAL NEURONS; NEURAL ACTIVITY; FIRE MODEL; IN-VITRO; VARIABILITY; DISTRIBUTIONS; COMPUTATION; NETWORKS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Feng, JF Babraham Inst, Computat Neurosci Lab, Cambridge CB2 4AT, England Babraham Inst Cambridge England CB2 4AT bridge CB2 4AT, England
Citazione:
J.F. Feng e D. Brown, "Coefficient of variation of interspike intervals greater than 0.5. How andwhen?", BIOL CYBERN, 80(5), 1999, pp. 291-297

Abstract

Using Stein's model with and without reversal potentials, we investigated the mechanism of production of spike trains with a CV (ISI) (standard deviation/mean interspike interval) greater than 0.5, as observed in the visual cortex. When the attractor of the deterministic part of the dynamics is below the firing threshold, spike generation results primarily from random fluctuations. Using computer simulation for a range of membrane decay times and with other model parameters set to values appropriate for the visual cortex, we demonstrate that CV (ISI) is then usually greater than 0.5; if the attractor is above the threshold, spike generation is mainly due to deterministic forces, and CV (ISI) is then usually lower than 0.5. The critical value of the inhibitory postsynaptic potential (IPSP) rate at which CV (ISI) becomes greater than 0.5 is determined, resulting in specifications of how neurones might adjust their synaptic inputs to elicit irregular spike trains.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:02:02