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Titolo:
Growth factors and their receptors in the olfactory system
Autore:
Plendl, J; Stierstorfer, B; Sinowatz, F;
Indirizzi:
Univnyunich, Tierarztliche Fak, Lehrstuhl Tieranat 2, D-80539 Munich, Germa Univ Munich Munich Germany D-80539 uhl Tieranat 2, D-80539 Munich, Germa Univ Munich, Tierarztliche Fak, Inst Physiol Chem, D-80539 Munich, GermanyUniv Munich Munich Germany D-80539 Physiol Chem, D-80539 Munich, Germany
Titolo Testata:
Anatomia, histologia, embryologia
fascicolo: 2, volume: 28, anno: 1999,
pagine: 73 - 79
SICI:
0340-2096(199905)28:2<73:GFATRI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
FACTOR BINDING-PROTEINS; RAT-BRAIN; MESSENGER-RNA; NGF-RECEPTOR; FACTOR-ALPHA; FACTOR-II; DIFFERENTIAL EXPRESSION; VOMERONASAL ORGAN; MOLECULAR-CLONING; CELL-DIVISION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
78
Recensione:
Indirizzi per estratti:
Indirizzo: Plendl, J Univunich,h, Tierarztliche Fak, Lehrstuhl Tieranat 2, Vet Str 13, D-80539 M Univ Munich Vet Str 13 Munich Germany D-80539 Str 13, D-80539 M
Citazione:
J. Plendl et al., "Growth factors and their receptors in the olfactory system", ANAT HISTOL, 28(2), 1999, pp. 73-79

Abstract

The olfactory epithelium is unique in the mammalian nervous system as it is a site of continual neurogenesis. Constant turnover of primary sensory neurons in the periphery results in continuous remodeling of neuronal circuits and synapses in the olfactory bulb throughout life. Most of the specific mechanisms and factors that control and modulate this process are not known. Recent studies suggest that growth factors, and their receptors, may playa crucial role in the development and continuous regeneration of olfactoryneurons, i.e. particularly in neuronal proliferation, neurite outgrowth, fasciculation and synapse formation of the olfactory system. The potential role of the following factors and their receptors in different species are reviewed: Nerve growth factor (NGF); insulin-like growth factors (IGFs); fibroblast growth factors (FGFs); epidermal growth factor (EGF); transforming growth factor alpha (TGF alpha); amphiregulin (AR) and transforming growth factors beta (TGFs beta).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 21:38:47