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Titolo:
Dobutamine stress thallium-201 single-photon emission tomography versus echocardiography for evaluation of the extent and location of coronary arterydisease late after myocardial infarction
Autore:
Elhendy, A; Bax, JJ; van Domburg, RT; Valkema, R; Cornel, JH; Reijs, AEM; Krenning, EP; Roelandt, JRTC;
Indirizzi:
Ctr Thorax, NL-3015 GD Rotterdam, Netherlands Ctr Thorax Rotterdam Netherlands NL-3015 GD 15 GD Rotterdam, Netherlands Erasmusdsniv, Hosp Dijkzigt, Dept Nucl Med, NL-3015 GD Rotterdam, Netherlan Erasmus Univ Rotterdam Netherlands NL-3015 GD 15 GD Rotterdam, Netherlan
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 5, volume: 26, anno: 1999,
pagine: 467 - 473
SICI:
0340-6997(199905)26:5<467:DSTSET>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPUTED-TOMOGRAPHY; HYPERTENSIVE PATIENTS; DIAGNOSTIC-ACCURACY; TL-201 TOMOGRAPHY; TETROFOSMIN; SPECT; SCINTIGRAPHY; REINJECTION; FEASIBILITY; ISCHEMIA;
Keywords:
dobutamine; echocardiography; thallium-201 single-photon emission tomography myocardial infarction; ischaemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Elhendy, A Ctr Thorax, Ba 302,Dr Molewaterplein 40, NL-3015 GD Rotterdam, Netherlands Ctr Thorax Ba 302,Dr Molewaterplein 40 Rotterdam Netherlands NL-3015 GD
Citazione:
A. Elhendy et al., "Dobutamine stress thallium-201 single-photon emission tomography versus echocardiography for evaluation of the extent and location of coronary arterydisease late after myocardial infarction", EUR J NUCL, 26(5), 1999, pp. 467-473

Abstract

Dobutamine stress echocardiography and thallium-201 myocardial perfusion scintigraphy are clinically useful methods for the evaluation of coronary artery disease (CAD), However, the relative merits of these imaging modalities in the evaluation of the extent of CAD after myocardial infarction have not been well studied. The aim of this study was to compare the accuracy of dobutamine stress echocardiography and simultaneous Tl-201 single-photon emission tomography (SPET) imaging for the diagnosis and localization of CAD late after acute myocardial infarction, Dobutamine (up to 40 mu g kg(-1) min(-1))-atropine (up to 1 mg) stress echocardiography in conjunction with stress-reinjection Tl-201 SPET was performed fur the evaluation of myocardialischaemia in 90 patients with previous myocardial infarction who underwentcoronary angiography. Significant CAD was predicted on bases of myocardialischemia (new or worsening wall motion abnormalities on echocardiography and reversible perfusion defects on Tl-201 SPET). Significant CAD (greater than or equal to 50% luminal diameter stenosis) was detected in 73 (81%) patients. The sensitivity, specificity and accuracy of echocardiography in detecting remote ischaemia for the diagnosis of remote CAD (present in 53 patients) were, respectively, 79% (CI 70%-88%), 85% (CT 77%-93%) and 81% (CI 73%-90%), while the corresponding figures for Tl-201 SPET were 75% (CI 66%-85%), 78% (CI 69%-87%) and 76% (CI 67%-86%) respectively (P = NS vs echocardiography). The sensitivity, specificity and accuracy of echocardiography in detecting peri-infarction ischaemia for the diagnosis of infarct-related artery stenosis (present in 70 patients) were, respectively, 77% (CI 68%-86%), 85% (CI 78%-92%) and 79% (CI 70%-87%) while the corresponding figures forTl-201 SPET were 73% (CI 64%-82%), 85% (CI 78%-92%) SPET were 73% (CI 78%-92%) and 76% (CI 67%-84%) respectively (P = NS vs echocardiography). The agreement between the two methods for the diagnosis of peri-infarction and remote ischaemia was 70% (kappa = 0.37) and 80% (kappa = 0.59) respectively. It is concluded that dobutamine stress echocardiography and Tl-201 SPET have comparable accuracy for the diagnosis of infarct related and remote CAD in patients with previous myocardial infarction. The agreement between the methods is higher for the diagnosis of remote CAD than for that of peri-infarction ischaemia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 00:50:12