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Titolo:
Pulse pressure, arterial compliance and cardiovascular morbidity and mortality
Autore:
Mitchell, GF;
Indirizzi:
Cardiovasc Engn Inc, Dover, MA 02030 USA Cardiovasc Engn Inc Dover MA USA02030 vasc Engn Inc, Dover, MA 02030 USA
Titolo Testata:
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
fascicolo: 3, volume: 8, anno: 1999,
pagine: 335 - 342
SICI:
1062-4821(199905)8:3<335:PPACAC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISOLATED SYSTOLIC HYPERTENSION; LEFT-VENTRICULAR HYPERTROPHY; AMBULATORY BLOOD-PRESSURE; INTIMA-MEDIA THICKNESS; DISEASE RISK-FACTORS; MYOCARDIAL-INFARCTION; AORTIC COMPLIANCE; CAROTID-ARTERY; CORONARY ATHEROSCLEROSIS; NORMOTENSIVE SUBJECTS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
88
Recensione:
Indirizzi per estratti:
Indirizzo: Mitchell, GF Cardiovasc Engn Inc, 3 Draper Rd, Dover, MA 02030 USA Cardiovasc Engn Inc 3 Draper Rd Dover MA USA 02030 02030 USA
Citazione:
G.F. Mitchell, "Pulse pressure, arterial compliance and cardiovascular morbidity and mortality", CURR OP NEP, 8(3), 1999, pp. 335-342

Abstract

Pulse pressure, an indicator of conduit vessel stiffness, has recently emerged as an important predictor of adverse cardiovascular events. The normally compliant conduit vessels provide an essential buffering role that minimizes potentially harmful pressure swings associated with intermittent pumping by the heart. A number of common conditions and acknowledged cardiac risk factors stiffen the conduit vessels, resulting in a vicious cycle of progressive vessel stiffening, increasing pulsatile load, pressure-related end-organ damage and clinical events. An emerging awareness of the central roleof conduit vessel stiffness in cardiovascular pathophysiology has important implications for the classification and treatment of hypertension and other disorders that affect conduit vessel function and pulsatile hemodynamics. Curr Opin Nephrol Hypertens 8:335-342. (C) 1999 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 01:57:28