Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PHOTOSENSITIVITY IN LUPUS-ERYTHEMATOSUS, UV PHOTOPROVOCATION RESULTS COMPARED WITH HISTORY OF PHOTOSENSITIVITY AND CLINICAL FINDINGS
Autore:
HASAN T; NYBERG F; STEPHANSSON E; PUSKA P; HAKKINEN M; SARNA S; ROS AM; RANKI A;
Indirizzi:
TAMPERE UNIV,DEPT DERMATOL,PL2000 FIN-33521 TAMPERE FINLAND TAMPERE UNIV HOSP FIN-33521 TAMPERE FINLAND KAROLINSKA HOSP & INST,DEPT DERMATOL STOCKHOLM SWEDEN UNIV HELSINKI,CENT HOSP,DEPT DERMATOL FIN-00170 HELSINKI FINLAND UNIV HELSINKI,DEPT PUBL HLTH HELSINKI FINLAND
Titolo Testata:
British journal of dermatology
fascicolo: 5, volume: 136, anno: 1997,
pagine: 699 - 705
SICI:
0007-0963(1997)136:5<699:PILUPR>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYMORPHOUS LIGHT ERUPTION; CUTANEOUS LUPUS; ANTINUCLEAR ANTIBODIES; SKIN-LESIONS; PREVALENCE; RADIATION; SPECTRUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
T. Hasan et al., "PHOTOSENSITIVITY IN LUPUS-ERYTHEMATOSUS, UV PHOTOPROVOCATION RESULTS COMPARED WITH HISTORY OF PHOTOSENSITIVITY AND CLINICAL FINDINGS", British journal of dermatology, 136(5), 1997, pp. 699-705

Abstract

Photosensitivity, one of the presenting symptoms in lupus erythematosus (LE), is still poorly defined and varying prevalence figures have been reported. The possibility of a coexisting photodermatosis, especially polymorphous light eruption (PLE), has often not been taken into account. We report the results of ultraviolet A (UVA) and B (UVB) photoprovocation tests in 67 clinically photosensitive patients who had confirmed discoid LE (DLE), systemic LE (SLE) or subacute cutaneous LE (SCLE). The results are compared with a detailed history of photosensitivity and with clinical and serological findings. A pathological photoprovocation reaction, graded as weak, moderate or strong, was induced with either UVA or UVB in 69% of patients with LE, in 100% of those with SCLE, in 70% of those with SLE and in 64% of those with DLE, but in none of 14 controls. Only 16% of the pathological reactions were strong and long-lasting, resembling LE lesions, while 48% were moderate or weak and transient, clinically like PLE. Fifty-three per cent of the provocation reactions which were biopsied showed a PLE-like histology or a non-specific inflammatory reaction, and most of them were clinically moderate or weak reactions of short duration. In the remaining, mostly clinically strong or long-lasting reactions, the histology was consistent with LE. A history of sunlight sensitivity did not predict a pathological photoprovocation result but a positive association betweenthe presence of SSA/Ro or SSB/La antibodies and a pathological photoprovocation reaction was found, We have shown that PLE coexists with LEand that both PLE- and LE-like lesions can be induced with UV radiation in LE patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:50:09