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Titolo:
ANTIPLATELET THERAPY ALONE IS SAFE AND EFFECTIVE AFTER CORONARY STENTING - OBSERVATIONS OF A TRANSITION IN PRACTICE
Autore:
ZUBAID M; PENN IM; BULLER CE; MOSCOVICH MD; RICCI DR; CHAUHAN A;
Indirizzi:
LAUREL INTERVENT CARDIOL RES,865 W 10TH AVE VANCOUVER BC V5Z 1L7 CANADA UNIV BRITISH COLUMBIA,VANCOUVER HOSP & HLTH SCI CTR VANCOUVER BC V5Z 1M9 CANADA
Titolo Testata:
Canadian journal of cardiology
fascicolo: 4, volume: 13, anno: 1997,
pagine: 335 - 340
SICI:
0828-282X(1997)13:4<335:ATAISA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PALMAZ-SCHATZ STENTS; ANGIOGRAPHIC FOLLOW-UP; INTRACORONARY ULTRASOUND; BALLOON ANGIOPLASTY; THREATENED CLOSURE; FAILED ANGIOPLASTY; ARTERY DISEASE; EXPERIENCE; IMPLANTATION; MULTICENTER;
Keywords:
ANTICOAGULATION; ANTIPLATELETS; STENTS; THROMBOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
M. Zubaid et al., "ANTIPLATELET THERAPY ALONE IS SAFE AND EFFECTIVE AFTER CORONARY STENTING - OBSERVATIONS OF A TRANSITION IN PRACTICE", Canadian journal of cardiology, 13(4), 1997, pp. 335-340

Abstract

OBJECTIVE: To evaluate the safety and efficacy of transition in practice after coronary stenting to antiplatelet therapy alone compared with anticoagulation with warfarin. DESIGN: Retrospective analysis of coronary stent management in a tertiary Canadian centre. PATIENTS: A total of 136 consecutive patients (146 lesions) were analyzed who underwent Palmaz-Schatz coronary stenting over a 15-month period and were treated with anticoagulation with warfarin (56 patients) or antiplatelet therapy alone with ticlopidine and acetylsalicylic acid (80 patients) during the transition in poststenting therapy in the authors' practice. Treatment was continued for 30 days in both groups. High pressure stent deployment was used in the majority of cases (greater than 90%), and use of intravascular ultrasound was infrequent (less than 12%). MAINRESULTS: At 30 days, there were no clinical manifestations of stent thrombosis, coronary artery bypass surgery or repeat angioplasty in either group. One death occurred in the antiplatelet group. Periprocedural non-Q wave myocardial infarction occurred in two patients in the antiplatelet group and in one patient in the warfarin group. There was a significantly higher incidence of vascular complications in the warfarin group than in the antiplatelet group (14.3% versus 2.5%, respectively, P=0.04). The length of hospital stay was significantly shorter in the antiplatelet group than in the warfarin group (3.0+/-1.8 versus 6.7+/-2.6 days, respectively, P<0.001). CONCLUSIONS: Reduced anticoagulation with antiplatelet therapy alone after coronary stenting, despite infrequent use of intravascular ultrasound, is an effective and safe strategy with a low rate of vascular complications, a relatively short hospital stay and a low incidence of clinical manifestations of stent thrombosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 18:56:31