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Titolo:
Blood flow compared in benign melanocytic naevi, malignant melanomas and basal cell carcinomas
Autore:
Stucker, M; Horstmann, I; Nuchel, C; Rochling, A; Hoffmann, K; Altmeyer, P;
Indirizzi:
Ruhr Univ Bochum, Dept Dermatol, D-44791 Bochum, Germany Ruhr Univ BochumBochum Germany D-44791 ermatol, D-44791 Bochum, Germany
Titolo Testata:
CLINICAL AND EXPERIMENTAL DERMATOLOGY
fascicolo: 2, volume: 24, anno: 1999,
pagine: 107 - 111
SICI:
0307-6938(199903)24:2<107:BFCIBM>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR PROGRESSION; ANGIOGENESIS; THERMOGRAPHY; VASCULARITY; PERFUSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Stucker, M Ruhr Univ Bochum, Dept Dermatol, Gudrunstr 56, D-44791 Bochum, Germany Ruhr Univ Bochum Gudrunstr 56 Bochum Germany D-44791 , Germany
Citazione:
M. Stucker et al., "Blood flow compared in benign melanocytic naevi, malignant melanomas and basal cell carcinomas", CLIN EXP D, 24(2), 1999, pp. 107-111

Abstract

Histologically, increasing malignancy is reflected by increased tumour vascularization, We therefore assessed whether laser Doppler perfusion imagingmight allow differentiation between different types of skin tumour. The perfusion patterns of 27 melanocytic naevi, 16 basal cell carcinomas and six malignant melanomas were examined with a laser Doppler perfusion imager before excision for precise diagnosis. Malignant melanomas were significantly more perfused than basal cell carcinomas and tended also to be more so thanmelanocytic naevi. Further, for the first time, the perfusion pattern of the entire tumour area was visualized two-dimensionally; it was higher in the centre of the tumours than at the periphery for malignant melanomas and melanocytic naevi but was the same throughout for basal cell carcinomas. Laser Doppler perfusion imaging can thus provide information to assist in the differential diagnosis of skin tumours, In addition, with increases in resolution of the technique such data may well become steadily more useful in the future.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/07/18 alle ore 13:14:48