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Titolo:
Precursors to schizophrenia: Do biological markers have specificity?
Autore:
Tarrant, CJ; Jones, PB;
Indirizzi:
Univ Nottingham, Div Psychiat, Nottingham NG3 6AA, England Univ Nottingham Nottingham England NG3 6AA , Nottingham NG3 6AA, England
Titolo Testata:
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
fascicolo: 4, volume: 44, anno: 1999,
pagine: 335 - 349
SICI:
0706-7437(199905)44:4<335:PTSDBM>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
MINOR PHYSICAL ANOMALIES; NEUROLOGICAL SOFT SIGNS; HIGH-RISK PROJECT; JERUSALEM INFANT DEVELOPMENT; POPULATION BIRTH COHORT; 28-YEAR FOLLOW-UP; PRENATAL EXPOSURE; AFFECTIVE-ILLNESS; MOOD DISORDERS; ABNORMALITIES;
Keywords:
schizophrenia; neurodevelopment; birth cohort; neurological soft signs; minor physical abnormalities; precursors; antecedents; specificity;
Tipo documento:
Reprint
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
103
Recensione:
Indirizzi per estratti:
Indirizzo: Tarrant, CJ Univghamtingham, Div Psychiat, Duncan Macmillan House,Porchester Rd, Nottin Univ Nottingham Duncan Macmillan House,Porchester Rd Nottingham England NG3 6AA
Citazione:
C.J. Tarrant e P.B. Jones, "Precursors to schizophrenia: Do biological markers have specificity?", CAN J PSY, 44(4), 1999, pp. 335-349

Abstract

This review addresses childhood antecedents and biological markers of schizophrenia within a neurodevelopmental framework. General-population birth-cohort studies illustrate delays in developmental milestones, abnormalities in social functioning, and cognitive deficits throughout childhood, adolescence and early adulthood. Abnormal neurology and motor dysfunction have been measured in children prior to the onset of schizophrenia, at first onset of disease, and in those with chronic schizophrenia. Minor physical anomalies, a static marker of developmental disturbance, are also increased in schizophrenia. None of these factors has high specificity for this disorder. This review examines the associations between these precursors and some etiological factors for schizophrenia, comments on their lack of complete specificity to this psychotic syndrome, and considers their usefulness as predictors of risk.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 02:15:03