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Titolo:
Imaging of subclinical atherosclerosis in children and young adults
Autore:
Raitakari, OT;
Indirizzi:
Royal Prince Alfred Hosp, Dept Cardiol, Sydney, NSW 2050, Australia Royal Prince Alfred Hosp Sydney NSW Australia 2050 y, NSW 2050, Australia Turku Univ, Dept Clin Physiol, Turku, Finland Turku Univ Turku FinlandTurku Univ, Dept Clin Physiol, Turku, Finland
Titolo Testata:
ANNALS OF MEDICINE
, volume: 31, anno: 1999, supplemento:, 1
pagine: 33 - 40
SICI:
0785-3890(199904)31:<33:IOSAIC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOTHELIUM-DEPENDENT DILATION; INTIMA-MEDIA THICKNESS; CORONARY-ARTERY DISEASE; PERIPHERAL CONDUIT ARTERIES; COMMON CAROTID-ARTERY; B-MODE ULTRASOUND; FAMILIAL HYPERCHOLESTEROLEMIA; FLOW RESERVE; RISK-FACTORS; CARDIOVASCULAR RISK;
Keywords:
atherosclerosis; noninvasive methods; preventive cardiology; vascular imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
59
Recensione:
Indirizzi per estratti:
Indirizzo: Raitakari, OT Royaltraliae Alfred Hosp, Dept Cardiol, Missenden Rd, Sydney, NSW 2050, Aus Royal Prince Alfred Hosp Missenden Rd Sydney NSW Australia 2050
Citazione:
O.T. Raitakari, "Imaging of subclinical atherosclerosis in children and young adults", ANN MED, 31, 1999, pp. 33-40

Abstract

Atherosclerosis begins in childhood and has a long preclinical phase before ischaemic symptoms appear. This provides an opportunity for subclinical detection of the disease and identification of high-risk subjects. Recent advances in imaging technology have identified many early functional and structural vascular changes, some of which may reflect subclinical atherosclerosis, and therefore provide areas of potential interest for diagnostic testsof preclinical atherosclerosis. These tarry events include changes in arterial vasodilatory function, alterations in arterial elasticity, thickening of arterial walls and calcification of atherosclerotic lesions. Clinical testing for presymptomatic atherosclerosis should involve methods that are safe, noninvasive, reliable and reproducible, and which correlate with the extent of the atherosclerotic process. Although no such tests are currently widely used in clinical practice, potential methods for detecting the processes outlined above include ultrasound, positron emission tomography, magnetic resonance imaging and ultrafast computed tomography. With further developments, noninvasive imaging techniques for the study of arterial function and structure may soon provide clinically useful ways of detecting early atherosclerosis in high-risk asymptomatic subjects at a stage where preventivestrategies are most likely to have important health benefits.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 12:22:37