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Titolo:
Elevation of serum cardiac troponin I in noncardiac and cardiac diseases other than acute coronary syndromes
Autore:
Khan, IA; Tun, A; Wattanasauwan, N; Win, MT; Hla, TA; Hussain, A; Vasavada, BC; Sacchi, TJ;
Indirizzi:
Long Isl Coll Hosp, Dept Med, Div Cardiol, Brooklyn, NY 11201 USA Long IslColl Hosp Brooklyn NY USA 11201 Cardiol, Brooklyn, NY 11201 USA
Titolo Testata:
AMERICAN JOURNAL OF EMERGENCY MEDICINE
fascicolo: 3, volume: 17, anno: 1999,
pagine: 225 - 229
SICI:
0735-6757(199905)17:3<225:EOSCTI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; CREATINE-KINASE-MB; CHRONIC-RENAL-FAILURE; ACUTE CHEST PAIN; HEART-FAILURE; DIAGNOSIS; MYOGLOBIN; INJURY; EMERGENCY; MARKERS;
Keywords:
cardiac troponin I; acute coronary syndromes; myocardial infarction; nonischemic cardiomyopathy; noncardiac diseases; muscular disorders; neurological disorders; HIV disease; chronic renal failure; sepsis; unstable angina;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Khan, IA 12 Vogel Loop, Staten Isl, NY 10314 USA 12 Vogel Loop Staten IslNY USA 10314 , Staten Isl, NY 10314 USA
Citazione:
I.A. Khan et al., "Elevation of serum cardiac troponin I in noncardiac and cardiac diseases other than acute coronary syndromes", AM J EMER M, 17(3), 1999, pp. 225-229

Abstract

This study evaluated the role of serum cardiac troponin I as a biochemicalmarker for the diagnosis of acute coronary syndromes in the presence of noncardiac diseases. Diagnostic characteristics were examined in 102 consecutive patients who were found to have serum cardiac troponin I levels higher than the upper reference limit of 0.6 ng/mL. Of 102 patients with cardiac troponin I levels of >0.6 ng/mL, 35 did not have the final diagnoses of acute coronary syndromes (myocardial infarction or unstable angina) but had various other final diagnoses, including nonischemic dilated cardiomyopathy, muscular disorders, central nervous system disorders, HIV disease, chronic renal failure, sepsis, lung diseases, and endocrine disorders. The mean value of serum cardiac troponin I in the patients with diseases other than acute coronary syndromes was significantly lesser than in those with acute coronary syndromes (2.0 +/- 1.9 [SD] v 24.7 +/- 28.2 ng/mL; P < .0001), There were significantly fewer histories of chest pain and prior myocardial infarction in patients with diseases other than acute coronary syndromes than in those with acute coronary syndromes (history of chest pain, 3 v 48 patients[P < .001]; history of prior myocardial infarction, 0 v 30 patients [P < .001]). In conclusion, elevated serum levels of cardiac troponin I, especially in the lower ranges, should be interpreted with caution, particularly inpatients suffering from acute illnesses who lack other diagnostic featuressuggestive of acute coronary ischemic events. Copyright (C) 1999 by W.B. Saunders Company.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 08:55:11