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Titolo:
Contrast transcranial Doppler ultrasound in the detection of right-to-leftshunts - Reproducibility, comparison of 2 agents, and distribution of microemboli
Autore:
Droste, DW; Reisener, M; Kemeny, V; Dittrich, R; Schulte-Altedorneburg, G; Stypmann, J; Wichter, T; Ringelstein, EB;
Indirizzi:
Univ Munster, Dept Neurol, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 Dept Neurol, D-4400 Munster, Germany Univ Munster, Dept Cardiol & Angiol, D-4400 Munster, Germany Univ MunsterMunster Germany D-4400 ol & Angiol, D-4400 Munster, Germany Univ Munster, Inst Arteriosclerosis Res, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 lerosis Res, D-4400 Munster, Germany
Titolo Testata:
STROKE
fascicolo: 5, volume: 30, anno: 1999,
pagine: 1014 - 1018
SICI:
0039-2499(199905)30:5<1014:CTDUIT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATENT FORAMEN OVALE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; CRYPTOGENIC STROKE; TRANSTHORACIC ECHOCARDIOGRAPHY; CEREBRAL-ISCHEMIA; VALSALVA MANEUVER; SURGICAL CLOSURE; SONOGRAPHY; RECURRENCE; EMBOLI;
Keywords:
cerebral embolism; cerebrovascular disorders; foramen ovale, patent; ultrasonography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Droste, DW WWUter,ster, Neurol Klin & Poliklin, Albert Schweitzer Str 33, D-48129 Muns WWU Munster Albert Schweitzer Str 33 Munster Germany D-48129 s
Citazione:
D.W. Droste et al., "Contrast transcranial Doppler ultrasound in the detection of right-to-leftshunts - Reproducibility, comparison of 2 agents, and distribution of microemboli", STROKE, 30(5), 1999, pp. 1014-1018

Abstract

Background and Purpose-Cardiac right-to-left shunts can be identified by transcranial Doppler ultrasound (TCD) with the use of different contrast agents and by transesophageal echocardiography (TEE). Systematic data are available on neither the reproducibility of contrast TCD, the comparison of different contrast agents, nor the comparison of simultaneous bilateral to unilateral recordings. Furthermore, we assessed the side distribution of thus provoked artificial cardiac emboli. Methods-Fifty-four patients were investigated by TEE and by bilateral TCD of the middle cerebral artery, The following protocol was performed twice: injection of 9 mL of agitated saline without Valsalva maneuver, injection of 9 mt of agitated saline with Valsalva maneuver, injection of 5 mL of a commercial galactose-based contrast agent without Valsalva maneuver, and injection of 5 mt of the galactose-based contrast agent with Valsalva maneuver. Results-In 18 patients, a right-to-left shunt was demonstrated by TEE and contrast TCD (shunt positive). Twenty-nine patients were negative in both investigations, 1 was positive on TEE and negative on TCD, and 6 patients were only positive on TCD. Both bilateral and repeated recordings increased the sensitivity of contrast TCD, There was a symmetrical distribution of microembolic signals in the right and left middle cerebral artery. Conclusions-TCD performed twice and with the use of saline or a galactose-based contrast agent is a sensitive method in the identification of cardiacright-to-left shunts also identified by TEE, The cardiac microemboli in this study did not show any side preference for one of the middle cerebral arteries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 12:05:04