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Titolo:
A radiation hybrid map of the rat genome containing 5,255 markers
Autore:
Watanabe, TK; Bihoreau, MT; McCarthy, LC; Kiguwa, SL; Hishigaki, H; Tsuji, A; Browne, J; Yamasaki, Y; Mizoguchi-Miyakita, A; Oga, K; Ono, T; Okuno, S; Kanemoto, N; Takahashi, E; Tomita, K; Hayashi, H; Adachi, M; Webber, C; Davis, M; Kiel, S; Knights, C; Smith, A; Critcher, R; Miller, J; Thangarajah, T; Day, PJR; Hudson, JR; Irie, Y; Takagi, T; Nakamura, Y; Goodfellow, PN; Lathrop, GM; Tanigami, A; James, MR;
Indirizzi:
Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England Wellcome Trust CtrHuman Genet Oxford England OX3 7BN d OX3 7BN, England Otsuka Pharmaceut Co Ltd, Otsuka GEN Res Inst, Tokushima 7710192, Japan Otsuka Pharmaceut Co Ltd Tokushima Japan 7710192 okushima 7710192, Japan Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England Univ Cambridge Cambridge England CB2 3EH net, Cambridge CB2 3EH, England Res Genet Inc, Huntsville, AL 35801 USA Res Genet Inc Huntsville AL USA 35801 Genet Inc, Huntsville, AL 35801 USA Univ Tokyo, Inst Med Sci, Mol Med Lab, Minato Ku, Tokyo 108, Japan Univ Tokyo Tokyo Japan 108 Sci, Mol Med Lab, Minato Ku, Tokyo 108, Japan
Titolo Testata:
NATURE GENETICS
fascicolo: 1, volume: 22, anno: 1999,
pagine: 27 - 36
SICI:
1061-4036(199905)22:1<27:ARHMOT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC-LINKAGE MAP; SPONTANEOUSLY HYPERTENSIVE RAT; ARTIFICIAL CHROMOSOME LIBRARY; DEPENDENT DIABETES-MELLITUS; BLOOD-PRESSURE; LABORATORY RAT; MOUSE GENOME; GK RAT; CONSTRUCTION; NORVEGICUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Tanigami, A Wellcome Trust Ctr Human Genet, Windmill Rd, Oxford OX3 7BN, England Wellcome Trust Ctr Human Genet Windmill Rd Oxford England OX3 7BN
Citazione:
T.K. Watanabe et al., "A radiation hybrid map of the rat genome containing 5,255 markers", NAT GENET, 22(1), 1999, pp. 27-36

Abstract

A whole-genome radiation hybrid (RH) panel was used to construct a high-resolution map of the rat genome based on microsatellite and gene markers. These include 3,019 new microsatellite markers described here for the first time and 1,714 microsatellite markers with known genetic locations, allowingcomparison and integration of maps from different sources. A robust RH framework map containing 1,030 positions ordered with odds of at least 1,000:1has been defined as a tool for mapping these markers, and for future RH mapping in the rat, More than 500 genes which have been mapped in mouse and/or human were localized with respect to the rat RH framework, allowing the construction of detailed rat-mouse and rat-human comparative maps and illustrating the power of the RH approach for comparative mapping.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 12:09:36