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Titolo:
Mediterranean diet improves better the lipid profile in smoking males thanthe American Cholesterol Program diet (NCEP-I)
Autore:
Sanchez, E; Jansen, S; Castro, P; Blanco, A; Lopez-Miranda, J; Fuentes, F; Lopez-Segura, F; Blanco, J; Jimenez-Pereperez, J; Perez-Jimenez, F;
Indirizzi:
HospordobaReina Sofia, Unidad Lipidos & Arteriosclerosis, Serv Anal Clin, C Hosp Univ Reina Sofia Cordoba Spain 14004 iosclerosis, Serv Anal Clin, C
Titolo Testata:
MEDICINA CLINICA
fascicolo: 6, volume: 112, anno: 1999,
pagine: 206 - 210
SICI:
0025-7753(19990220)112:6<206:MDIBTL>2.0.ZU;2-U
Fonte:
ISI
Lingua:
SPA
Soggetto:
CORONARY HEART-DISEASE; DENSITY-LIPOPROTEIN-CHOLESTEROL; CIGARETTE-SMOKING; SERUM-LIPIDS; PLASMA; ACID; MECHANISMS; RISK; FAT; MEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Perez-Jimenez, F HospvenidaReina Sofia, Unidad Lipidos & Arteriosclerosis,Serv Anal Clin, A Hosp Univ Reina Sofia Avenida Menendez Pidal S-N Cordoba Spain 14004
Citazione:
E. Sanchez et al., "Mediterranean diet improves better the lipid profile in smoking males thanthe American Cholesterol Program diet (NCEP-I)", MED CLIN, 112(6), 1999, pp. 206-210

Abstract

BACKGROUND: A study Of the efect of smokers' diets on their atherogenic lipidic profile. SUBJECTS AND METHODS: 41 healthy males (32 non-smokers and 9 smokers) consumed consecutively a diet low in fat and rich in carbohydrates (28% total fat content < 10% saturated fats, and 57% carbohydrates), and a diet rich inmonounsaturated fatty acids (38% total fat content with 22% monounsaturated fats). At the end of each dietary period, adhesion was confirmed by quantification of LDL cholesterol esters, plasma lipids and insulin levels. RESULTS: There were no significant differences between the age or the bodymass of the groups of smokers or non-smokers, After both diets tobacco wasfound to have a significant effect on triglyceride levels (p < 0.0007), HDLc (p < 0.007), apo A-I (p < 0.02) and the LDLc/HDLc ratio (p < 0.005), revealing an interaction between diet and both HDLc levels (p < 0.004) and LDLc/HDLc ratios (p < 0.003). With the low fat and high monounsaturated fatty acid content diets smokers presented higher triglyceride levels (both with p < 0.0002) and LDLc/HDLc ratios (p < 0.0002 and p < 0.05, respectively) and lower levels of apo A-I (p < 0.002 and p < 0.004, respectively). However,in smokers the HDLc levels were only reduced after the low fat diet (p < 0.0003) and after the diet with a high monounsaturated fat content there wasa rise in HDLc levels (p < 0.02) and a drop in the LDLc/HDLc ratio (p < 0.005) compared to the group of non-smokers. There were no significant differences in the insulin levels between groups. CONCLUSION: The atherogenic lipidic profile of smokers is due to an effectof tobacco on the lipidic metabolism. This atherogenic profile is accentuated with a low fat diet rich in carbohydrates and can he rectified to some degree with a diet with a high monounsaturated fatty acid content.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 03:51:30